Clonal multidrug-resistant Corynebacterium striatum within a nosocomial environment, Rio de Janeiro, Brazil

被引：51

作者：

Pereira Baio, Paulo Victor ^{[1
,4
,5
]}

Mota, Higor Franceschi ^{[1
]}

Freitas, Andrea D'avila ^{[1
,2
]}

Rama Gomes, Debora Leandro ^{[1
,6
]}

Ramos, Juliana Nunes ^{[1
,4
]}

Sant'Anna, Lincoln Oliveira ^{[1
]}

Souza, Monica Cristina ^{[1
]}

Ferreira Camello, Thereza Cristina ^{[1
,3
]}

Hirata Junior, Raphael ^{[1
]}

Vieira, Veronica Viana ^{[4
]}

Mattos-Guaraldi, Ana Luiza ^{[1
]}

机构：

[1] Univ Estado Rio de Janeiro, Hosp Univ Pedro Ernesto, Fac Ciencias Med, Lab Difteria & Corinebacterias Importancia Clin,D, BR-20550011 Rio De Janeiro, RJ, Brazil

[2] Univ Estado Rio de Janeiro, Hosp Univ Pedro Ernesto, Unidade Docente Assistencial Doencas Infecciosas, BR-20550011 Rio De Janeiro, RJ, Brazil

[3] Univ Estado Rio de Janeiro, Hosp Univ Pedro Ernesto, Bacteriol Lab, BR-20550011 Rio De Janeiro, RJ, Brazil

[4] Fiocruz MS, Dept Microbiol, Inst Nacl Controle Qualidade Saude, BR-21045900 Rio De Janeiro, RJ, Brazil

[5] Minist Def, Lab Quim Farmaceut Exercito, Rio De Janeiro, RJ, Brazil

[6] Inst Fed Educ Ciencia & Tecnol Rio de Janeiro, Fac Farm, Rio De Janeiro, RJ, Brazil

来源：

MEMORIAS DO INSTITUTO OSWALDO CRUZ | 2013年 / 108卷 / 01期

关键词：

Corynebacterium striatum; nosocomial outbreak; PFGE; multidrug-resistant clones; IDENTIFICATION; STRAIN; INFECTIONS; EMERGENCE; BOVIS;

D O I：

10.1590/S0074-02762013000100004

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Corynebacterium striatum is a potentially pathogenic microorganism with the ability to produce outbreaks of nosocomial infections. Here, we document a nosocomial outbreak caused by multidrug-resistant (MDR) C. striatum in Rio de Janeiro, Brazil. C. striatum identification was confirmed by 16S rRNA and rpoB gene sequencing. Fifteen C. striatum strains were isolated from adults (half of whom were 50 years of age and older). C. striatum was mostly isolated in pure culture from tracheal aspirates of patients undergoing endotracheal intubation procedures. The analysis by pulsed-field gel electrophoresis (PFGE) indicated the presence of four PFGE profiles, including two related clones of MDR strains (PFGE I and II). The data demonstrated the predominance of PFGE type I, comprising 11 MDR isolates that were mostly isolated from intensive care units and surgical wards. A potential causal link between death and MDR C. striatum (PFGE types I and II) infection was observed in five cases.

引用

页码：23 / 29

页数：7

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