Routine surveillance for symptomatic toxicities with real-time clinician reporting in Danish breast cancer patients-Organization and design of the first national, cluster randomized trial using the Patient-Reported Outcomes version of Common Terminology Criteria for Adverse Events (PRO-CTCAE)

被引：12

作者：

Pappot, Helle ^{[1
]}

Baeksted, Christina ^{[1
,2
]}

Knoop, Ann ^{[1
]}

Mitchell, Sandra A. ^{[3
]}

Nissen, Aase ^{[2
]}

Johansen, Christoffer ^{[4
]}

机构：

[1] Rigshosp, Finsen Ctr, Dept Oncol, Copenhagen, Denmark

[2] Danish Canc Soc, Documentat & Qual, Copenhagen, Denmark

[3] NCI, Outcomes Res Branch, Div Canc Control & Populat Sci, Rockville, MD USA

[4] Danish Canc Soc Res Ctr, Unit Survivorship, Copenhagen, Denmark

来源：

BREAST JOURNAL | 2019年 / 25卷 / 02期

关键词：

adjuvant chemotherapy; breast cancer; patient reported outcome; PRO-CTCAE; toxicity; FOLLOW-UP;

D O I：

10.1111/tbj.13204

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The Patient-Reported Outcomes version of Common Terminology Criteria for Adverse Events (PRO-CTCAE) was developed by the National Cancer Institute to capture patient self-reports of symptomatic toxicities during cancer treatment. The aim of this short communication is to describe the design of a national study, which examine the effect of using patients' electronic PRO-CTCAE reporting with real-time feedback to clinicians on treatment events for breast cancer patients receiving adjuvant chemotherapy. The study's end-points are defined as dose reduction, hospitalization, and febrile neutropenia. This is the first report on the impact of PRO-CTCAE in a national breast cancer population during chemotherapy treatment.

引用

页码：269 / 272

页数：4