Stromal exosomes allow cancer cell autoactivation

被引：4

作者：

Fellouse, Frederic A. ^{[1
]}

机构：

[1] Mt Sinai Hosp, Lunenfeld Tanenbaum Res Inst, Toronto, ON M5G 1X5, Canada

来源：

M S-MEDECINE SCIENCES | 2014年 / 30卷 / 04期

关键词：

D O I：

10.1051/medsci/20143004014

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Exosomes are small vesicles derived from endosomes and carrying several constituants of the cell; if captured by other neighbour cell types, they can trigger novel functions in these cells. We illustrate here (through recently published results) how exosomes released by activated tumor-associated fibroblasts are able to induce in cancer cells a signalling pathway key to the acquisition of motility and hence metastatic property.

引用

页码：405 / 407

页数：3

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