Primary and Secondary Immune Cytopenias Evaluation and Treatment Approach in Children

被引：17
作者：
Kim, Taylor Olmsted [1 ]
Despotovic, Jenny M. [2 ]
机构：
[1] Texas Childrens Canc & Hematol Ctr, Baylor Coll Med, Pediat Hematol Oncol, 1102 Bates Ave,Suite 1025-06, Houston, TX 77030 USA
[2] Texas Childrens Canc & Hematol Ctr, Baylor Coll Med, Pediat Hematol Oncol, 6701 Fannin St,Suite 1580, Houston, TX 77070 USA
来源：
HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 2019年 / 33卷 / 03期
关键词：
Autoimmune cytopenias; Thrombocytopenia; ITP; Hemolytic anemia; AIHA; AUTOIMMUNE HEMOLYTIC-ANEMIA; LYMPHOPROLIFERATIVE SYNDROME; THROMBOCYTOPENIC PURPURA; RITUXIMAB THERAPY; BONE-MARROW; ELTROMBOPAG; MANAGEMENT; DIAGNOSIS; MULTICENTER; EFFICACY;
D O I：
10.1016/j.hoc.2019.01.005
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
This review summarizes the evaluation and management of the autoimmune cytopenias, a heterogeneous group of conditions including, but not limited to, autoimmune hemolytic anemia, immune thrombocytopenia, and multilineage disorders in Evans syndrome. These diseases can be challenging to treat and there are limited data comparing second-line therapeutics. The understanding of the molecular cause of these conditions is improving with the goal of advancing therapies and making them more targeted.
引用
收藏
页码：489 / +
页数：19
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