Osteoarthritis of the knee

被引：578
作者：
Felson, DT [1 ]
机构：
[1] Boston Univ, Sch Med, Boston, MA 02118 USA
来源：
NEW ENGLAND JOURNAL OF MEDICINE | 2006年 / 354卷 / 08期
关键词：
D O I：
10.1056/NEJMcp051726
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A 66-year-old woman who is overweight reports bilateral knee pain of gradual onset during the past several months that increasingly has limited her activities. Last week, when walking down the stairs, she nearly fell when her knee gave way. She does not recall having injured her knee, and she has no morning stiffness and no pain in other joints. She has tried taking up to eight extra-strength ( 500 mg each) acetaminophen tablets daily without success and has never had ulcers or stomach bleeding. How should the patient be evaluated and treated?
引用
收藏
页码：841 / 848
页数：8
相关论文
共 52 条
[31]  
HURLEY MV, 1993, BRIT J RHEUMATOL, V32, P127
[32]   Effectiveness of a lateral-wedge insole on knee varus torque in patients with knee osteoarthritis [J].
Kerrigan, DC ;
Lelas, JL ;
Goggins, J ;
Merriman, GJ ;
Kaplan, RJ ;
Felson, DT .
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION, 2002, 83 (07) :889-893
[33]   The effect of bracing on varus gonarthrosis [J].
Kirkley, A ;
Webster-Bogaert, S ;
Litchfield, R ;
Amendola, A ;
MacDonald, S ;
McCalden, R ;
Fowler, P .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 1999, 81A (04) :539-548
[34]   Intra-articular hyaluronic acid in treatment of knee osteoarthritis - A meta-analysis [J].
Lo, GH ;
LaValley, M ;
McAlindon, T ;
Felson, DT .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2003, 290 (23) :3115-3121
[35]   Laterally elevated wedged insoles in the treatment of medial knee osteoarthritis: a prospective randomized controlled study [J].
Maillefert, JF ;
Hudry, C ;
Baron, G ;
Kieffert, P ;
Bourgeois, P ;
Lechevalier, D ;
Coutaux, A ;
Dougados, M .
OSTEOARTHRITIS AND CARTILAGE, 2001, 9 (08) :738-745
[36]   Effectiveness of glucosamine for symptoms of knee osteoarthritis: Results from an Internet-based randomized double-blind controlled trial [J].
McAlindon, T ;
Formica, M ;
LaValley, M ;
Lehmer, M ;
Kabbara, K .
AMERICAN JOURNAL OF MEDICINE, 2004, 117 (09) :643-649
[37]   RADIOGRAPHIC PATTERNS OF OSTEOARTHRITIS OF THE KNEE-JOINT IN THE COMMUNITY - THE IMPORTANCE OF THE PATELLOFEMORAL JOINT [J].
MCALINDON, TE ;
SNOW, S ;
COOPER, C ;
DIEPPE, PA .
ANNALS OF THE RHEUMATIC DISEASES, 1992, 51 (07) :844-849
[38]   Glucosamine and chondroitin for treatment of osteoarthritis - A systematic quality assessment and meta-analysis [J].
McAlindon, TE ;
LaValley, MP ;
Gulin, JP ;
Felson, DT .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2000, 283 (11) :1469-1475
[39]   Exercise and dietary weight loss in overweight and obese older adults with knee osteoarthritis - The arthritis, diet, and activity promotion trial [J].
Messier, SP ;
Loeser, RF ;
Miller, GD ;
Morgan, TM ;
Rejeski, WJ ;
Sevick, MA ;
Ettinger, WH ;
Pahor, M ;
Williamson, J .
ARTHRITIS AND RHEUMATISM, 2004, 50 (05) :1501-1510
[40]   A controlled trial of arthroscopic surgery for osteoarthritis of the knee [J].
Moseley, JB ;
O'Malley, K ;
Petersen, NJ ;
Menke, TJ ;
Brody, BA ;
Kuykendall, DH ;
Hollingsworth, JC ;
Ashton, CM ;
Wray, NP .
NEW ENGLAND JOURNAL OF MEDICINE, 2002, 347 (02) :81-88
123456