Tunable sheathless microfluidic focusing using ion concentration polarization

被引:7
作者
Yoon, Junghyo [1 ]
Cho, Youngkyu [2 ]
Lee, Jeong Hoon [3 ]
Chung, Seok [1 ]
机构
[1] Korea Univ, Sch Mech Engn, Seoul 136701, South Korea
[2] Korea Univ, Dept IT Convergence, Seoul 136701, South Korea
[3] Kwangwoon Univ, Dept Elect Engn, Seoul 139701, South Korea
基金
新加坡国家研究基金会;
关键词
ACOUSTIC-WAVES SSAW; CHANNEL; MICROCHANNELS; SEPARATION;
D O I
10.1063/1.4929816
中图分类号
O59 [应用物理学];
学科分类号
摘要
In this study, we developed a tunable sheathiess focusing method for focusing micrometer- and nanometer-sized particles, using ion concentration polarization (ICP) in an ion-selective, resin-coated channel. The particle movement was regulated using an electric field, and by varying the flow rate and ionic strength of the liquid solution; various phenomena were observed, depending on the particle properties. Here, we provide insights into the physical basis of the ICP-focusing phenomena, and a statistical approach for analyzing the particle movement. This ICP-focusing technology is an approach that could be applied for the separation and sorting of various particles, including cells, proteins, and bacteria. (C) 2015 AIP Publishing LLC.
引用
收藏
页数:5
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