Tunable sheathless microfluidic focusing using ion concentration polarization

被引：7

作者：

Yoon, Junghyo ^{[1
]}

Cho, Youngkyu ^{[2
]}

Lee, Jeong Hoon ^{[3
]}

Chung, Seok ^{[1
]}

机构：

[1] Korea Univ, Sch Mech Engn, Seoul 136701, South Korea

[2] Korea Univ, Dept IT Convergence, Seoul 136701, South Korea

[3] Kwangwoon Univ, Dept Elect Engn, Seoul 139701, South Korea

来源：

APPLIED PHYSICS LETTERS | 2015年 / 107卷 / 08期

基金：

新加坡国家研究基金会;

关键词：

ACOUSTIC-WAVES SSAW; CHANNEL; MICROCHANNELS; SEPARATION;

D O I：

10.1063/1.4929816

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

In this study, we developed a tunable sheathiess focusing method for focusing micrometer- and nanometer-sized particles, using ion concentration polarization (ICP) in an ion-selective, resin-coated channel. The particle movement was regulated using an electric field, and by varying the flow rate and ionic strength of the liquid solution; various phenomena were observed, depending on the particle properties. Here, we provide insights into the physical basis of the ICP-focusing phenomena, and a statistical approach for analyzing the particle movement. This ICP-focusing technology is an approach that could be applied for the separation and sorting of various particles, including cells, proteins, and bacteria. (C) 2015 AIP Publishing LLC.

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页数：5

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