Genetic risk factors in Parkinson's disease: single gene effects and interactions of genotypes

被引：7

作者：

Goebel, Anna ^{[1
]}

Macklin, Eric A. ^{[2
]}

Winkler, Susen ^{[1
]}

Betensky, Rebecca A. ^{[3
]}

Klein, Christine ^{[1
]}

Lohmann, Katja ^{[1
]}

Simon, David K. ^{[4
]}

机构：

[1] Med Univ Lubeck, Dept Neurol, Sect Clin & Mol Neurogenet, D-23538 Lubeck, Germany

[2] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Ctr Biostat, Boston, MA USA

[3] Harvard Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02115 USA

[4] Harvard Univ, Sch Med, Dept Neurol, Beth Israel Beaconess Ctr, Boston, MA 02115 USA

来源：

JOURNAL OF NEUROLOGY | 2012年 / 259卷 / 11期

关键词：

PATHOGENESIS; ROLES;

D O I：

10.1007/s00415-012-6623-2

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

引用

页码：2503 / 2505

页数：3

共 13 条

[1] Milestones in PD Genetics [J].

Gasser, Thomas ;

Hardy, John ;

Mizuno, Yoshikuni .

MOVEMENT DISORDERS, 2011, 26 (06) :1042-1048

[2] THE RELEVANCE OF THE LEWY BODY TO THE PATHOGENESIS OF IDIOPATHIC PARKINSONS-DISEASE [J].

GIBB, WRG ;

LEES, AJ .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1988, 51 (06) :745-752

[3]

Golqb-Janowska M, 2007, NEUROL NEUROCHIR POL, V41, P388

[4] Brief Update on Different Roles of Tau in Neurodegeneration [J].

Ittner, Arne ;

Ke, Yazi D. ;

van Eersel, Janet ;

Gladbach, Amadeus ;

Goetz, Juergen ;

Ittner, Lars M. .

IUBMB LIFE, 2011, 63 (07) :495-502

[5] A web server for inferring the human N-acetyltransferase-2 (NAT2) enzymatic phenotype from NAT2 genotype [J].

Kuznetsov, Igor B. ;

McDuffie, Michael ;

Moslehi, Roxana .

BIOINFORMATICS, 2009, 25 (09) :1185-1186

[6] The S18Y polymorphic variant of UCH-L1 confers an antioxidant function to neuronal cells [J].

Kyratzi, Elli ;

Pavlaki, Maria ;

Stefanis, Leonidas .

HUMAN MOLECULAR GENETICS, 2008, 17 (14) :2160-2171

[7] Comprehensive Research Synopsis and Systematic Meta-Analyses in Parkinson's Disease Genetics: The PDGene Database [J].

Lill, Christina M. ;

Roehr, Johannes T. ;

McQueen, Matthew B. ;

Kavvoura, Fotini K. ;

Bagade, Sachin ;

Schjeide, Brit-Maren M. ;

Schjeide, Leif M. ;

Meissner, Esther ;

Zauft, Ute ;

Allen, Nicole C. ;

Liu, Tian ;

Schilling, Marcel ;

Anderson, Kari J. ;

Beecham, Gary ;

Berg, Daniela ;

Biernacka, Joanna M. ;

Brice, Alexis ;

DeStefano, Anita L. ;

Do, Chuong B. ;

Eriksson, Nicholas ;

Factor, Stewart A. ;

Farrer, Matthew J. ;

Foroud, Tatiana ;

Gasser, Thomas ;

Hamza, Taye ;

Hardy, John A. ;

Heutink, Peter ;

Hill-Burns, Erin M. ;

Klein, Christine ;

Latourelle, Jeanne C. ;

Maraganore, Demetrius M. ;

Martin, Eden R. ;

Martinez, Maria ;

Myers, Richard H. ;

Nalls, Michael A. ;

Pankratz, Nathan ;

Payami, Haydeh ;

Satake, Wataru ;

Scott, William K. ;

Sharma, Manu ;

Singleton, Andrew B. ;

Stefansson, Kari ;

Toda, Tatsushi ;

Tung, Joyce Y. ;

Vance, Jeffery ;

Wood, Nick W. ;

Zabetian, Cyrus P. ;

Young, Peter ;

Tanzi, Rudolph E. ;

Khoury, Muin J. .

PLOS GENETICS, 2012, 8 (03)

[8]

Lill CM, PDGENE DATABASE

[9] Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies [J].

Nalls, Michael A. ;

Plagnol, Vincent ;

Hernandez, Dena G. ;

Sharma, Manu ;

Sheerin, Una-Marie ;

Saad, Mohamad ;

Simon-Sanchez, Javier ;

Schulte, Claudia ;

Lesage, Suzanne ;

Sveinbjornsdottir, Sigurlaug ;

Arepalli, Sampath ;

Barker, Roger ;

Ben-Shlomo, Yoav ;

Berendse, Henk W. ;

Berg, Daniela ;

Bhatia, Kailash ;

de Bie, Rob M. A. ;

Biffi, Alessandro ;

Bloem, Bas ;

Bochdanovits, Zoltan ;

Bonin, Michael ;

Bras, Jose M. ;

Brockmann, Kathrin ;

Brooks, Janet ;

Burn, David J. ;

Charlesworth, Gavin ;

Chen, Honglei ;

Chinnery, Patrick F. ;

Chong, Sean ;

Clarke, Carl E. ;

Cookson, Mark R. ;

Cooper, J. Mark ;

Corvol, Jean Christophe ;

Counsell, Carl ;

Damier, Philippe ;

Dartigues, Jean-Francois ;

Deloukas, Panos ;

Deuschl, Guenther ;

Dexter, David T. ;

van Dijk, Karin D. ;

Dillman, Allissa ;

Durif, Frank ;

Duerr, Alexandra ;

Edkins, Sarah ;

Evans, Jonathan R. ;

Foltynie, Thomas ;

Gao, Jianjun ;

Gardner, Michelle ;

Gibbs, J. Raphael ;

Goate, Alison .

LANCET, 2011, 377 (9766) :641-649

[10] A Two-Stage Meta-Analysis Identifies Several New Loci for Parkinson's Disease [J].

Plagnol, Vincent ;

Nalls, Michael A. ;

Bras, Jose M. ;

Hernandez, Dena G. ;

Sharma, Manu ;

Sheerin, Una-Marie ;

Saad, Mohamad ;

Simon-Sanchez, Javier ;

Schulte, Claudia ;

Lesage, Suzanne ;

Sveinbjornsdottir, Sigurlaug ;

Amouyel, Philippe ;

Arepalli, Sampath ;

Band, Gavin ;

Barker, Roger A. ;

Bellinguez, Celine ;

Ben-Shlomo, Yoav ;

Berendse, Henk W. ;

Berg, Daniela ;

Bhatia, Kailash ;

de Bie, Rob M. A. ;

Biffi, Alessandro ;

Bloem, Bas ;

Bochdanovits, Zoltan ;

Bonin, Michael ;

Brockmann, Kathrin ;

Brooks, Janet ;

Burn, David J. ;

Charlesworth, Gavin ;

Chen, Honglei ;

Chinnery, Patrick F. ;

Chong, Sean ;

Clarke, Carl E. ;

Cookson, Mark R. ;

Cooper, J. Mark ;

Corvol, Jean Christophe ;

Counsell, Carl ;

Damier, Philippe ;

Dartigues, Jean-Francois ;

Deloukas, Panos ;

Deuschl, Guenther ;

Dexter, David T. ;

van Dijk, Karin D. ;

Dillman, Allissa ;

Durif, Frank ;

Duerr, Alexandra ;

Edkins, Sarah ;

Evans, Jonathan R. ;

Foltynie, Thomas ;

Freeman, Colin .

PLOS GENETICS, 2011, 7 (06)

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