Clinical significance of right hepatectomy along the main portal fissure on donors in living donor liver transplantation

被引:2
作者
Kim, Bong-Wan [1 ]
Park, Yong-Keun [1 ]
Xu, Weiguang [1 ]
Wang, Hee-Jung [1 ]
Lee, Jae-Myeong [1 ]
Lee, Kwangil [1 ]
机构
[1] Ajou Univ, Dept Hepatobiliary Surg & Liver Transplantat, Sch Med, Suwon 443749, South Korea
关键词
donor safety; living donor liver transplantation; main portal fissure; right hepatectomy; MIDDLE HEPATIC VEIN; RIGHT-LOBE; GRAFT; COMPLICATIONS; EXPERIENCE; FAILURE; IMPACT; SAFETY;
D O I
10.1111/j.1432-2277.2012.01538.x
中图分类号
R61 [外科手术学];
学科分类号
摘要
There might be discordance between inter-lobar borders of the main portal fissure (MPF) using the middle hepatic vein (MHV) and of the portal segmentation. Forty-five living donors who underwent right hepatectomy for the adult recipients from 2007 to 2011 in a tertiary hospital were retrospectively analyzed. The donors were classified into conventional right hepatectomy along the MPF (cRL group, n = 26) and modified right hepatectomy along right-side shifted transection plane from the MPF (mRL group, n = 19). The cRL donors had higher postoperative peak level of INR (1.84 vs. 1.62; P = 0.022), and bilirubin (3.37 mg/dl vs. 2.74 mg/dl; P = 0.065) than the mRL donors. cRL donors experienced greater depression of platelet count (144 per nL vs. 168 per nL; P = 0.042) and enlargement of splenic volume (52% vs. 37%; P = 0.025) than mRL donors for 7 days after hepatectomy. The regeneration of the left lateral sector was more accelerated in the cRL donors than the mRL donors for postoperative 3 months (148% vs. 84%; P = 0.015). There were no differences in the post-transplant graft function, incidence of complications, and graft survival rates between the two groups of recipients (P > 0.05). This study suggests that the conventional right hepatectomy along the MHV might increase donor risk by reducing parenchymal liver volume of the segment IV.
引用
收藏
页码:1072 / 1083
页数:12
相关论文
共 50 条
  • [41] Measures for increasing the safety of donors in living donor liver transplantation using right lobe grafts
    Wen, Tian-Fu
    Chen, Zhe-Yu
    Yan, Lu-Nan
    Li, Bo
    Zeng, Yong
    Zhao, Ji-Chun
    Wang, Wen-Tho
    Yang, Jia-Yin
    Ma, Yu-Kui
    Xu, Ming-Qing
    Liu, Jiang-Wen
    Deng, Zhi-Gang
    Wu, Hong
    HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL, 2007, 6 (06) : 590 - 595
  • [42] TRANSPLANTATION Minimizing the risks for living donors of right lobe liver grafts
    Egawa, Hiroto
    NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY, 2011, 8 (05) : S251 - 252
  • [43] Feasibility and outcomes of living-donor liver transplantation utilizing the right hemi-liver graft with portal vein anatomical variations
    Shehta, Ahmed
    Elshobari, Mohamed
    Salah, Tarek
    Sultan, Ahmad M.
    Yasen, Amr
    Shiha, Usama
    El-Saadany, Mohamed
    Monier, Ahmed
    Said, Rami
    Habl, Mohamed S.
    Adly, Reham
    El Ged, Basma Abd Elmoaem
    Karam, Rasha
    Khaled, Reem
    El Razek, Hassan Magdy Abd
    Abdel-Khalek, Ehab E.
    Wahab, Mohamed Abdel
    LANGENBECKS ARCHIVES OF SURGERY, 2023, 408 (01)
  • [44] Right Lobe Living-Donor Liver Transplantation With or Without Middle Hepatic Vein: A Meta-Analysis
    Zhang, S.
    Dong, Z.
    Zhang, M.
    Xia, Q.
    Liu, D.
    Zhang, J. J.
    TRANSPLANTATION PROCEEDINGS, 2011, 43 (10) : 3773 - 3779
  • [45] Indications and results of right-lobe living donor liver transplantation
    Vella, Ivan
    di Francesco, Fabrizio
    Accardo, Caterina
    Boggi, Ugo
    Gruttadauria, Salvatore
    UPDATES IN SURGERY, 2024,
  • [46] Outcomes of living donor liver transplantation using elderly donors
    Han, Jae Hyun
    You, Young Kyoung
    Na, Gun Hyung
    Kim, Eun Young
    Lee, Soo Ho
    Hong, Tae Ho
    Kim, Dong Goo
    ANNALS OF SURGICAL TREATMENT AND RESEARCH, 2014, 86 (04) : 184 - 191
  • [47] Outcome of Right Hepatectomy for Living Liver Donors: A Single Egyptian Center Experience
    Tarek Salah
    Ahmad M. Sultan
    Omar M. Fathy
    Mohammed M. Elshobary
    Nabieh A. Elghawalby
    Ahmed Sultan
    Amr M. Yassen
    Walid M. R. Elsarraf
    Mohammed Elmorshedi
    Mohammed F. Elsaadany
    Usama A. Shiha
    M. Abdel Wahab
    Journal of Gastrointestinal Surgery, 2012, 16 : 1181 - 1188
  • [48] Criteria for selecting living liver donors to optimize recipient outcomes in pure laparoscopic donor right hepatectomy: a cohort study
    Hong, Suk Kyun
    Hong, Su young
    Lee, Jeong-Moo
    Choi, Youngrok
    Yi, Nam-Joon
    Lee, Kwang-Woong
    Suh, Kyung-Suk
    INTERNATIONAL JOURNAL OF SURGERY, 2024, 110 (06) : 3203 - 3211
  • [49] Respiratory complications:: A major concern after right hepatectomy in living liver donors
    Dondero, F
    Taillé, C
    Mal, H
    Sommacale, D
    Sauvanet, A
    Farges, O
    Francoz, C
    Durand, F
    Delefosse, D
    Denninger, MH
    Vilgrain, V
    Marrash-Chahla, R
    Fournier, M
    Belghiti, J
    TRANSPLANTATION, 2006, 81 (02) : 181 - 186
  • [50] Is right lobe liver graft without main right hepatic vein suitable for living donor liver transplantation?
    Demyati, Khaled
    Akbulut, Sami
    Cicek, Egemen
    Dirican, Abuzer
    Koc, Cemalettin
    Yilmaz, Sezai
    WORLD JOURNAL OF HEPATOLOGY, 2020, 12 (07) : 406 - 412