Lyapunov functions and global stability for SIR and SIRS epidemiological models with non-linear transmission

被引:291
作者
Korobeinikov, Andrei [1 ]
机构
[1] Hokkaido Univ, Res Inst Elect Sci, Lab Nonlinear Sci & Computat, Sapporo, Hokkaido 0600812, Japan
基金
日本学术振兴会;
关键词
direct Lyapunov method; Lyapunov function; endemic equilibrium state; global stability; nonlinear incidence;
D O I
10.1007/s11538-005-9037-9
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Lyapunov functions for two-dimension SIR and SIRS compartmental epidemic models with non-linear transmission rate of a very general form f(S. I) constrained by a few biologically feasible conditions are constructed. Global properties of these models including these with vertical and horizontal transmission, are thereby established. It is proved that, under the constant population size assumption, the concavity of the function f(S. I) with respect to the number of the infective hosts I ensures the uniqueness and the global stability of the positive endemic equilibrium state.
引用
收藏
页码:615 / 626
页数:12
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