Neoadjuvant procarbazine, CCNU, and vincristine for anaplastic and aggressive oligodendroglioma

被引：54
作者：
Paleologos, NA
Macdonald, DR
Vick, NA
Cairncross, JG
机构：
[1] Northwestern Univ, Evanston Hosp, Div Neurol, Evanston, IL 60201 USA
[2] London Reg Canc Ctr, London, ON N6A 4L6, Canada
来源：
NEUROLOGY | 1999年 / 53卷 / 05期
关键词：
oligodendroglioma; chemotherapy; neoadjuvant;
D O I：
10.1212/WNL.53.5.1141
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The authors reviewed the results of neoadjuvant (preradiation) procarbazine, CCNU, and vincristine chemotherapy for anaplastic oligodendrogliomas because, increasingly, chemotherapy is prescribed before radiation for oligodendroglial neoplasms. The data indicate that 70% of patients respond to neoadjuvant chemotherapy, whereas 30% require early radiation because they either have chemoresistant tumors or experience unacceptable chemotoxicity.
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收藏
页码：1141 / 1143
页数：3
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