Electric field control of ordered oxygen vacancy planes and antiferromagnetic structures in strontium cobaltite

The polarized ionic liquids (ILs) could generate intense electric fields on the surface of solid-state materials and create functional defects by ion migration within them, resulting in phase transitions of metal-insulator or paramagnet-ferromagnet, etc. Such a strong electric field even provides an opportunity for the control of spin ordering in antiferromagnetic (AFM) crystal which is difficult to be manipulated due to the strong exchange coupling between antiparallel spins in the whole bulk. Here we find that the ferromagnetic SrCoO3 of 40 nm could be transformed to AFM SrCoO2.5 with ordered oxygen vacancy planes either vertical (V-SrCoO2.5) or parallel (P-SrCoO2.5) to the surface by IL gating. The spin Hall magnetoresistances suggest that the AFM easy axes of V- and P-SrCoO2.5 are along [010] and 11 over bar 0= 3 times) were reported in 11 patients receiving both valproate and clobazam. AEs were significantly higher at M2 (p= 0.03) and increased with the number of AEDs (p= 0.03). At M6, total seizure frequency change from baseline was -41% +/- 37.5% (mean +/- standard deviation), and 28 patients (37.8%) had a reduction >= 50%. AE and efficacy did not differ between DS vs. LGS and CLB+ vs. CLB- patients. Significance:A slower titration of CBD dose delivered better tolerance with comparable efficacy to previous trials. Concomitant CLB did not increase efficacy rates but in a few cases increased AEs. This slow titration scheme should help guide clinicians prescribing CBD and allow patients to benefit from its potential efficacy.