Dramatic Response to Crizotinib in a Patient With Lung Cancer Positive for an HLA-DRB1-MET Gene Fusion

被引：61

作者：

Davies, Kurtis D. ^{[1
]}

Ng, Terry L. ^{[1
]}

Estrada-Bernal, Adriana ^{[1
]}

Le, Anh T. ^{[1
]}

Ennever, Peter R. ^{[2
]}

Camidge, D. Ross ^{[1
]}

Doebele, Robert C. ^{[1
]}

Aisner, Dara L. ^{[1
]}

机构：

[1] Univ Colorado, Anschutz Med Campus, Aurora, CO USA

[2] Cone Hlth Canc Ctr, Greensboro, NC USA

来源：

JCO PRECISION ONCOLOGY | 2017年 / 1卷

关键词：

D O I：

10.1200/PO.17.00117

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

[No abstract available]

引用

页码：1 / 6

页数：6

共 22 条

[1] Impaired c-Met Receptor Degradation Mediated by MET Exon 14 Mutations in Non-Small-Cell Lung Cancer [J].

Awad, Mark M. .

JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (08) :879-+

[2] Recurrent MET fusion genes represent a drug target in pediatric glioblastoma [J].

Bender, Sebastian ;

Gronych, Jan ;

Warnatz, Hans-Joerg ;

Hutter, Barbara ;

Groebner, Susanne ;

Ryzhova, Marina ;

Pfaff, Elke ;

Hovestadt, Volker ;

Weinberg, Florian ;

Halbach, Sebastian ;

Kool, Marcel ;

Northcott, Paul A. ;

Sturm, Dominik ;

Bjerke, Lynn ;

Zichner, Thomas ;

Stutz, Adrian M. ;

Schramm, Kathrin ;

Huang, Bingding ;

Buchhalter, Ivo ;

Heinold, Michael ;

Risch, Thomas ;

Worst, Barbara C. ;

van Tilburg, Cornelis M. ;

Weber, Ursula D. ;

Zapatka, Marc ;

Raeder, Benjamin ;

Milford, David ;

Heiland, Sabine ;

von Kalle, Christof ;

Previti, Christopher ;

Lawerenz, Chris ;

Kulozik, Andreas E. ;

Unterberg, Andreas ;

Witt, Olaf ;

von Deimling, Andreas ;

Capper, David ;

Truffaux, Nathalene ;

Grill, Jacques ;

Jabado, Nada ;

Sehested, Astrid M. ;

Sumerauer, David ;

Hmida-Ben Brahim, Dorra ;

Trabelsi, Saoussen ;

Ng, Ho-Keung ;

Zagzag, David ;

Allen, Jeffrey C. ;

Karajannis, Matthias A. ;

Gottardo, Nicholas G. ;

Jones, Chris ;

Korbel, Jan .

NATURE MEDICINE, 2016, 22 (11) :1314-1320

[3] Resistance to ROS1 Inhibition Mediated by EGFR Pathway Activation in Non-Small Cell Lung Cancer [J].

Davies, Kurtis D. ;

Mahale, Sakshi ;

Astling, David P. ;

Aisner, Dara L. ;

Le, Anh T. ;

Hinz, Trista K. ;

Vaishnavi, Aria ;

Bunn, Paul A., Jr. ;

Heasley, Lynn E. ;

Tan, Aik-Choon ;

Camidge, D. Ross ;

Varella-Garcia, Marileila ;

Doebele, Robert C. .

PLOS ONE, 2013, 8 (12)

[4] Cabozantinib in patients with advanced RET-rearranged non-small-cell lung cancer: an open-label, single-centre, phase 2, single-arm trial [J].

Drilon, Alexander ;

Rekhtman, Natasha ;

Arcila, Maria ;

Wang, Lu ;

Ni, Andy ;

Albano, Melanie ;

Van Voorthuysen, Martine ;

Somwar, Romel ;

Smith, Roger S. ;

Montecalvo, Joseph ;

Plodkowski, Andrew ;

Ginsberg, Michelle S. ;

Riely, Gregory J. ;

Rudin, Charles M. ;

Ladanyi, Marc ;

Kris, Mark G. .

LANCET ONCOLOGY, 2016, 17 (12) :1653-1660

[5] Durable Clinical Response to Entrectinib in NTRK1-Rearranged Non-Small Cell Lung Cancer [J].

Farago, Anna F. ;

Le, Long P. ;

Zheng, Zongli ;

Muzikansky, Alona ;

Drilon, Alexander ;

Patel, Manish ;

Bauer, Todd M. ;

Liu, Stephen V. ;

Ou, Sai-Hong I. ;

Jackman, David ;

Costa, Daniel B. ;

Multani, Pratik S. ;

Li, Gary G. ;

Hornby, Zachary ;

Chow-Maneval, Edna ;

Luo, David ;

Lim, Jonathan E. ;

Iafrate, Anthony J. ;

Shaw, Alice T. .

JOURNAL OF THORACIC ONCOLOGY, 2015, 10 (12) :1670-1674

[6] Activation of MET via Diverse Exon 14 Splicing Alterations Occurs in Multiple Tumor Types and Confers Clinical Sensitivity to MET Inhibitors [J].

Frampton, Garrett M. ;

Ali, Siraj M. ;

Rosenzweig, Mark ;

Chmielecki, Juliann ;

Lu, Xinyuan ;

Bauer, Todd M. ;

Akimov, Mikhail ;

Bufill, Jose A. ;

Lee, Carrie ;

Jentz, David ;

Hoover, Rick ;

Ou, Sai-Hong Ignatius ;

Salgia, Ravi ;

Brennan, Tim ;

Chalmers, Zachary R. ;

Jaeger, Savina ;

Huang, Alan ;

Elvin, Julia A. ;

Erlich, Rachel ;

Fichtenholtz, Alex ;

Gowen, Kyle A. ;

Greenbowe, Joel ;

Johnson, Adrienne ;

Khaira, Depinder ;

McMahon, Caitlin ;

Sanford, Eric M. ;

Roels, Steven ;

White, Jared ;

Greshock, Joel ;

Schlegel, Robert ;

Lipson, Doron ;

Yelensky, Roman ;

Morosini, Deborah ;

Ross, Jeffrey S. ;

Collisson, Eric ;

Peters, Malte ;

Stephens, Philip J. ;

Miller, Vincent A. .

CANCER DISCOVERY, 2015, 5 (08) :850-859

[7] EGFR Fusions as Novel Therapeutic Targets in Lung Cancer [J].

Konduri, Kartik ;

Gallant, Jean-Nicolas ;

Chae, Young Kwang ;

Giles, Francis J. ;

Gitlitz, Barbara J. ;

Gowen, Kyle ;

Ichihara, Eiki ;

Owonikoko, Taofeek K. ;

Peddareddigari, Vijay ;

Ramalingam, Suresh S. ;

Reddy, Satyanarayan K. ;

Eaby-Sandy, Beth ;

Vavala, Tiziana ;

Whiteley, Andrew ;

Chen, Heidi ;

Yan, Yingjun ;

Sheehan, Jonathan H. ;

Meiler, Jens ;

Morosini, Deborah ;

Ross, Jeffrey S. ;

Stephens, Philip J. ;

Miller, Vincent A. ;

Ali, Siraj M. ;

Lovly, Christine M. .

CANCER DISCOVERY, 2016, 6 (06) :601-611

[8] Molecular Testing Guideline for Selection of Lung Cancer Patients for EGFR and ALK Tyrosine Kinase Inhibitors Guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology [J].

Lindeman, Neal I. ;

Cagle, Philip T. ;

Beasley, Mary Beth ;

Chitale, Dhananjay Arun ;

Dacic, Sanja ;

Giaccone, Giuseppe ;

Jenkins, Robert Brian ;

Kwiatkowski, David J. ;

Saldivar, Juan-Sebastian ;

Squire, Jeremy ;

Thunnissen, Erik ;

Ladanyi, Marc .

JOURNAL OF MOLECULAR DIAGNOSTICS, 2013, 15 (04) :415-453

[9] Molecular characteristics of non-small cell lung cancer [J].

Nacht, M ;

Dracheva, T ;

Gao, YH ;

Fujii, T ;

Chen, YD ;

Player, A ;

Akmaev, V ;

Cook, B ;

Dufault, M ;

Zhang, M ;

Zhang, W ;

Guo, MZ ;

Curran, J ;

Han, S ;

Sidransky, D ;

Buetow, K ;

Madden, SL ;

Jen, J .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (26) :15203-15208

[10] Activity of Crizotinib (PF02341066), a Dual Mesenchymal-Epithelial Transition (MET) and Anaplastic Lymphoma Kinase (ALK) Inhibitor, in a Non-small Cell Lung Cancer Patient with De Novo MET Amplification [J].

Ou, Sai-Hong Ignatius ;

Kwak, Eunice L. ;

Siwak-Tapp, Christina ;

Dy, Joni ;

Bergethon, Kristin ;

Clark, Jeffrey W. ;

Camidge, D. Ross ;

Solomon, Benjamin J. ;

Maki, Robert G. ;

Bang, Yung-Jue ;

Kim, Dong-Wan ;

Christensen, James ;

Tan, Weiwei ;

Wilner, Keith D. ;

Salgia, Ravi ;

Iafrate, A. John .

JOURNAL OF THORACIC ONCOLOGY, 2011, 6 (05) :942-946

← 1 2 3 →