Structure and evolution of the extended B7 family

被引：86

作者：

Henry, J

Miller, MM

Pontarotti, P

机构：

[1] Fac Med Limoges, CNRS, ER1794, F-87025 Limoges, France

[2] INSERM, U119, F-13009 Marseille, France

[3] City Hope Natl Med Ctr, Beckman Res Inst, Duarte, CA 91010 USA

来源：

IMMUNOLOGY TODAY | 1999年 / 20卷 / 06期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/S0167-5699(98)01418-2

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Here, Joelle Henry and colleagues explore structural and evolutionary relationships between the B7 costimulator molecules and a growing number of molecules encoded within the major. histocompatibility complex. They propose that B7 and MHC genes are derived from it common ancestor, with several members of this large gene family possibly having pivotal influences on T-cell activation.

引用

收藏

页码：285 / 288

页数：4

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