Modern developments in molecular replacement

被引：18
作者：
Turkenburg, JP
Dodson, EJ
机构：
[1] Chemistry Department, University of York, Heslington
来源：
CURRENT OPINION IN STRUCTURAL BIOLOGY | 1996年 / 6卷 / 05期
关键词：
D O I：
10.1016/S0959-440X(96)80025-X
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Molecular replacement is a possible route to obtaining initial phasing for an unknown structure from a known, structurally related molecule. Recent years have seen an explosive growth in the number of protein structures solved using this technique. Automated packages can make the application quite straightforward. Progress has been made in the placing of fragments of complexes, and in the use of imprecise models from NMR or homology modelling. Such models have necessitated the development of new approaches to rebuilding and refinement.
引用
收藏
页码：604 / 610
页数：7
相关论文
共 53 条
  • [21] THE CRYSTAL-STRUCTURE OF HUMAN ENDOTHELIN
    JANES, RW
    PEAPUS, DH
    WALLACE, BA
    [J]. NATURE STRUCTURAL BIOLOGY, 1994, 1 (05): : 311 - 319
  • [22] CRYSTAL-STRUCTURES OF CELLULAR RETINOIC ACID-BINDING PROTEIN-I AND PROTEIN-II IN COMPLEX WITH ALL-TRANS-RETINOIC ACID AND A SYNTHETIC RETINOID
    KLEYWEGT, GJ
    BERGFORS, T
    SENN, H
    LEMOTTE, P
    GSELL, B
    SHUDO, K
    JONES, TA
    [J]. STRUCTURE, 1994, 2 (12) : 1241 - 1258
  • [23] ROTATIONAL SEARCH PROCEDURE FOR DETECTING A KNOWN MOLECULE IN A CRYSTAL
    LATTMAN, EE
    LOVE, WE
    [J]. ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL CRYSTALLOGRAPHY AND CRYSTAL CHEMISTRY, 1970, B 26 (NOV15): : 1854 - &
  • [24] CRYSTAL-STRUCTURE OF A SOLUBLE FORM OF THE HUMAN T-CELL CORECEPTOR CD8 AT 2.6 A-RESOLUTION
    LEAHY, DJ
    AXEL, R
    HENDRICKSON, WA
    [J]. CELL, 1992, 68 (06) : 1145 - 1162
  • [25] Crystallization and preliminary X-ray analysis of twinned crystals of a chimeric FK506 binding protein 12 and 13 complexed with FK506
    Liang, J
    Ealick, S
    Nielsen, C
    Schreiber, SL
    Clardy, J
    [J]. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, 1996, 52 : 207 - 210
  • [26] MACHIN PA, 1985, MOL REPLACEMENT
  • [27] CRYSTAL-STRUCTURE OF A SUICIDAL DNA-REPAIR PROTEIN - THE ADA O-6-METHYLGUANINE-DNA METHYLTRANSFERASE FROM ESCHERICHIA-COLI
    MOORE, MH
    GULBIS, JM
    DODSON, EJ
    DEMPLE, B
    MOODY, PCE
    [J]. EMBO JOURNAL, 1994, 13 (07) : 1495 - 1501
  • [28] STRUCTURE DETERMINATION OF COXSACKIEVIRUS B3 TO 3.5 ANGSTROM RESOLUTION
    MUCKELBAUER, JK
    KREMER, M
    MINOR, I
    TONG, L
    ZLOTNICK, A
    JOHNSON, JE
    ROSSMANN, MG
    [J]. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, 1995, 51 : 871 - 887
  • [29] HUMAN INTERLEUKIN-4 AND VARIANT R88Q - PHASING X-RAY-DIFFRACTION DATA BY MOLECULAR REPLACEMENT USING X-RAY AND NUCLEAR-MAGNETIC-RESONANCE MODELS
    MULLER, T
    OEHLENSCHLAGER, F
    BUEHNER, M
    [J]. JOURNAL OF MOLECULAR BIOLOGY, 1995, 247 (02) : 360 - 372
  • [30] MURSHUDOV G, 1996, IN PRESS REFINEMENT
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