Postural Orthostatic Tachycardia Syndrome JACC Focus Seminar

被引:157
作者
Bryarly, Meredith [1 ]
Phillips, Lauren T. [1 ]
Fu, Qi [2 ,3 ]
Vernino, Steven [1 ]
Levine, Benjamin D. [2 ,3 ]
机构
[1] Univ Texas Southwestern Med Ctr Dallas, Dept Neurol & Neurotherapeut, Dallas, TX 75390 USA
[2] Texas Hlth Presbyterian Hosp, Inst Exercise & Environm Med, Dallas, TX USA
[3] Univ Texas Southwestern Med Ctr Dallas, Div Cardiol, Dallas, TX 75390 USA
关键词
orthostatic intolerance; postural orthostatic tachycardia syndrome; POTS; syncope; tachycardia; SYMPATHETIC NEURAL RESPONSES; BED-REST; HEMODYNAMIC-RESPONSES; CARDIAC ATROPHY; GENERALIZED HYPERVIGILANCE; CONSENSUS STATEMENT; HEART-RATE; INTOLERANCE; HYPOTENSION; WOMEN;
D O I
10.1016/j.jacc.2018.11.059
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Postural orthostatic tachycardia syndrome (POTS), the most common form of orthostatic intolerance in young people, affects approximately 500,000 people in the United States alone, typically young women at the peak of their education and the beginning of their working lives. This is a heterogeneous disorder, the pathophysiology and mechanisms of which are not well understood. There are multiple contributing factors and numerous potential mimics. This review details the most current views on the potential causes, comorbid conditions, proposed subtypes, differential diagnoses, evaluations, and treatment of POTS from cardiological and neurological perspectives. (J Am Coll Cardiol 2019; 73: 1207- 28) (c) 2019 by the American College of Cardiology Foundation.
引用
收藏
页码:1207 / 1228
页数:22
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