Non-motor symptoms of Parkinson's disease

被引：42

作者：

Hou, Jyh-Gong Gabriel ^{[1
]}

Lai, Eugene C. ^{[1
]}

机构：

[1] Baylor Coll Med, Parkinsons Dis Res Educ & Clin Ctr, Michael E DeBakey VA Med Ctr, Houston, TX 77030 USA

来源：

INTERNATIONAL JOURNAL OF GERONTOLOGY | 2007年 / 1卷 / 02期

关键词：

dementia; depression; dysautonomia; non-motor symptoms; Parkinson's disease; psychosis; sleep; RESTLESS LEGS SYNDROME; EXCESSIVE DAYTIME SLEEPINESS; SILDENAFIL CITRATE VIAGRA; CONTROLLED CLINICAL-TRIAL; MULTIPLE SYSTEM ATROPHY; DOUBLE-BLIND; ORTHOSTATIC HYPOTENSION; AUTONOMIC DYSFUNCTION; LEWY BODIES; ERECTILE DYSFUNCTION;

D O I：

10.1016/S1873-9598(08)70024-3

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

In addition to the typical motor symptoms (resting tremor, cogwheel rigidity, bradykinesia, postural instability) of Parkinson's disease (PD), non-motor symptoms are sources of considerable burden in people with PD, especially in elderly patients. The usual non-motor symptoms include cognitive declines, psychiatric disturbances (depression, psychosis, impulse control), autonomic failures (gastrointestinal, cardiovascular, urinary, sexual ability, thermoregulation), sleep difficulties, and pain syndrome. This review article discusses the characteristics, pathophysiology, epidemiology, and management of these symptoms.

引用

页码：53 / 64

页数：12

共 126 条

[1] Prevalence and characteristics of dementia in Parkinson disease - An 8-year prospective study [J].