A highly regioselective sp3 C-H amination of tertiary amides based on Fe(II) complex catalysts

被引：28
作者：
Mao, Xuerong [1 ]
Wu, Yuanzhao [1 ]
Jiang, Xiaoxiang [1 ]
Liu, Xunhua [1 ]
Cheng, Yixiang [1 ]
Zhu, Chengjian [1 ]
机构：
[1] Nanjing Univ, Key Lab Mesoscop Chem MOE, Sch Chem & Chem Engn, Nanjing 210093, Jiangsu, Peoples R China
来源：
RSC ADVANCES | 2012年 / 2卷 / 17期
基金：
中国国家自然科学基金;
关键词：
BOND FORMATION; AMIDATION; NITROGEN; FUNCTIONALIZATION; ADJACENT; ACTIVATION; ELECTRON; ACCESS; AZOLES;
D O I：
10.1039/c2ra20707a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A highly regioselective sp(3) C-H amination of aryl amides with N-substituted pyrrolidin-2-ones has been developed with a catalyst Fe(II) complex with TBHP as a benign oxidant. This facile method can offer rapid access to the amination reaction of N-substituted pyrrolidin-2-ones in moderate to excellent yields.
引用
收藏
页码：6733 / 6735
页数：3
相关论文
共 44 条
  • [1] Tetrabutylammonium Decatungstate (Chemo)selective Photocatalyzed, Radical C-H Functionalization in Amides
    Angioni, Simone
    Ravelli, Davide
    Emma, Daniele
    Dondi, Daniele
    Fagnoni, Maurizio
    Albini, Angelo
    [J]. ADVANCED SYNTHESIS & CATALYSIS, 2008, 350 (14-15) : 2209 - 2214
  • [2] [Anonymous], 2008, ANGEW CHEM
  • [3] Direct Azole Amination: C-H Functionalization as a New Approach to Biologically Important Heterocycles
    Armstrong, Alan
    Collins, James C.
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (13) : 2282 - 2285
  • [4] A Comparative Mechanistic Study of Cu-Catalyzed Oxidative Coupling Reactions with N-Phenyltetrahydroisoquinoline
    Boess, Esther
    Schmitz, Corinna
    Klussmann, Martin
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2012, 134 (11) : 5317 - 5325
  • [5] Catalytic C-H amination: recent progress and future directions
    Collet, Florence
    Dodd, Robert H.
    Dauban, Philippe
    [J]. CHEMICAL COMMUNICATIONS, 2009, (34) : 5061 - 5074
  • [6] Kinetic versus thermodynamic access to imidazoisoindolones, benzimidazoisoindolones, and [1,4]diazepinoisoindolones:: intramolecular nitrogen and π-aromatic trapping of N-acyliminium cation
    Cul, A
    Daïch, A
    Decroix, B
    Sanz, G
    Van Hijfte, L
    [J]. TETRAHEDRON, 2004, 60 (48) : 11029 - 11039
  • [7] Recent advances in catalytic intramolecular C-H aminations
    Davies, HML
    Long, MS
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2005, 44 (23) : 3518 - 3520
  • [8] Espino CG, 2001, ANGEW CHEM INT EDIT, V40, P598, DOI 10.1002/1521-3773(20010202)40:3<598::AID-ANIE598>3.0.CO
  • [9] 2-9
  • [10] Synthesis of 1,3-difunctionalized amine derivatives through selective C-H bond oxidation
    Espino, CG
    Wehn, PM
    Chow, J
    Du Bois, J
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (28) : 6935 - 6936
12345