Frequency of Gestational Diabetes Mellitus at Collaborating Centers Based on IADPSG Consensus Panel-Recommended Criteria The Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study

被引:583
作者
Sacks, David A. [2 ]
Hadden, David R. [3 ]
Maresh, Michael [4 ]
Deerochanawong, Chaicharn [5 ]
Dyer, Alan R. [6 ]
Metzger, Boyd E. [1 ]
Lowe, Lynn P. [6 ]
Coustan, Donald R. [7 ]
Hod, Moshe [8 ]
Oats, Jeremy J. N. [9 ]
Persson, Bengt [10 ]
Trimble, Elisabeth R. [11 ]
机构
[1] Northwestern Univ, Feinberg Sch Med, Div Endocrinol Metab & Mol Med, Chicago, IL 60611 USA
[2] Kaiser Fdn Hosp, Dept Obstet & Gynecol, Bellflower, CA USA
[3] Royal Victoria Hosp, Reg Ctr Endocrinol & Diabet, Belfast BT12 6BA, Antrim, North Ireland
[4] Cent Manchester Univ Hosp, Dept Obstet, St Marys Hosp Women, Manchester, Lancs, England
[5] Rajavithi Hosp, Rangsit Med Sch, Dept Diabet & Endocrinol, Bangkok, Thailand
[6] Northwestern Univ, Feinberg Sch Med, Dept Prevent Med, Chicago, IL 60611 USA
[7] Brown Univ, Div Maternal Fetal Med, Women & Infants Hosp Rhode Isl, Alpert Med Sch, Providence, RI 02912 USA
[8] Tel Aviv Univ, Dept Obstet & Gynecol, Helen Schneider Hosp Women, Rabin Med Ctr,Sackler Fac Med, Petah Tiqwa, Israel
[9] Univ Queensland, Dept Obstet Med, Mater Misericordiae Mothers Hosp, Brisbane, Qld, Australia
[10] Karolinska Inst, Dept Pediat, S-10401 Stockholm, Sweden
[11] Queens Univ Belfast, Dept Clin Biochem, Belfast, Antrim, North Ireland
关键词
D O I
10.2337/dc11-1641
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVE-To report frequencies of gestational diabetes mellitus (GDM) among the 15 centers that participated in the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study using the new International Association of the Diabetes and Pregnancy Study Groups (IADPSG) criteria. RESEARCH DESIGN AND METHODS-All participants underwent a 75-g oral glucose tolerance test between 24 and 32 weeks' gestation. GDM was retrospectively classified using the IADPSG criteria (one or more fasting, 1-h, or 2-h plasma glucose concentrations equal to or greater than threshold values of 5.1, 10.0, or 8.5 mmol/L, respectively). RESULTS-Overall frequency of GDM was 17.8% (range 9.3-25.5%). There was substantial center-to-center variation in which glucose measures met diagnostic thresholds. CONCLUSIONS-Although the new diagnostic criteria for GDM apply globally, center-to-center differences occur in GDM frequency and relative diagnostic importance of fasting, 1-h, and 2-h glucose levels. This may impact strategies used for the diagnosis of GDM.
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收藏
页码:526 / 528
页数:3
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