The multiple challenges of neuropathic pain

被引：23

作者：

Bouhassira, Didier ^{[1
]}

Attal, Nadine ^{[1
]}

机构：

[1] Ambroise Pare Hosp, APHP, Inserm, U987, F-92100 Boulogne, France

来源：

NEUROSCIENCE LETTERS | 2019年 / 702卷

关键词：

Clinical research; Assessment; Treatment; Diagnosis; CENTRAL POSTSTROKE PAIN; POSTHERPETIC NEURALGIA; CENTRAL SENSITIZATION; GRADING SYSTEM; DOUBLE-BLIND; GABAPENTIN; DIAGNOSIS; EFFICACY; OSTEOARTHRITIS; FIBROMYALGIA;

D O I：

10.1016/j.neulet.2018.11.054

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Over the last three decades, the number of research studies devoted to neuropathic pain has increased dramatically. This expansion of knowledge has generated a number of challenges, mostly relating to revisions of the definition of neuropathic pain, its diagnosis, the development of new analgesics based on mechanisms investigated in animals, and the development of optimal therapeutic approaches in clinical trials. This review focuses on these multiple challenges and proposes some topics for reflection.

引用

页码：6 / 10

页数：5

共 44 条

[1] Diagnosis and assessment of neuropathic pain through questionnaires [J].

Attal, Nadine ;

Bouhassira, Didier ;

Baron, Ralf .

LANCET NEUROLOGY, 2018, 17 (05) :456-466

[2] Safety and efficacy of repeated injections of botulinum toxin A in peripheral neuropathic pain (BOTNEP): a randomised, double-blind, placebo-controlled trial [J].

Attal, Nadine ;

de Andrade, Daniel C. ;

Adam, Frederic ;

Ranoux, Daniele ;

Teixeira, Manoel J. ;

Galhardoni, Ricardo ;

Raicher, Irina ;

Ueceyler, Nurcan ;

Sommer, Claudia ;

Bouhassira, Didier .

LANCET NEUROLOGY, 2016, 15 (06) :555-565

[3] Gabapentin for the symptomatic treatment of painful neuropathy in patients with diabetes mellitus - A randomized controlled trial [J].

Backonja, M ;

Beydoun, A ;

Edwards, KR ;

Schwartz, SL ;

Fonseca, V ;

Hes, M ;

LaMoreaux, L ;

Garofalo, E .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1998, 280 (21) :1831-1836

[4] Nociception, Pain, Negative Moods, and Behavior Selection [J].

Baliki, Marwan N. ;

Apkarian, A. Vania .

NEURON, 2015, 87 (03) :474-491

[5] Multiple sites and actions of gabapentin-induced relief of ongoing experimental neuropathic pain [J].

Bannister, Kirsty ;

Qu, Chaoling ;

Navratilova, Edita ;

Oyarzo, Janice ;

Xie, Jennifer Yanhua ;

King, Tamara ;

Dickenson, Anthony H. ;

Porreca, Frank .

PAIN, 2017, 158 (12) :2386-2395

[6] Subgrouping of patients with neuropathic pain according to pain-related sensory abnormalities: a first step to a stratified treatment approach [J].

Baron, Ralf ;

Foerster, Matti ;

Binder, Andreas .

LANCET NEUROLOGY, 2012, 11 (11) :999-1005

[7] Neuropathic pain: diagnosis, pathophysiological mechanisms, and treatment [J].

Baron, Ralf ;

Binder, Andreas ;

Wasner, Gunnar .

LANCET NEUROLOGY, 2010, 9 (08) :807-819

[8] TRANSLATIONAL NEUROPATHIC PAIN RESEARCH: A CLINICAL PERSPECTIVE [J].

Bouhassira, D. ;

Attal, N. .

NEUROSCIENCE, 2016, 338 :27-35

[9] Prevalence of chronic pain with neuropathic characteristics in the general population [J].

Bouhassira, Didier ;

Lanteri-Minet, Michel ;

Attal, Nadine ;

Laurent, Bernard ;

Touboul, Chantal .

PAIN, 2008, 136 (03) :380-387

[10] Emerging therapies for neuropathic pain: new molecules or new indications for old treatments? [J].

Bouhassira, Didier ;

Attal, Nadine .

PAIN, 2018, 159 (03) :576-582

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