Copper catalyzed oxygen assisted C(CNOH)-C(alkyl)bond cleavage: a facile conversion of aryl/aralkyl/vinyl ketones to aromatic acids

被引：25

作者：

Sathyanarayana, Pochampalli ^{[1
]}

Ravi, Owk ^{[1
]}

Muktapuram, Prathap Reddy ^{[1
]}

Bathula, Surendar Reddy ^{[1
]}

机构：

[1] Indian Inst Chem Technol, CSIR, Div Nat Prod Chem, Hyderabad 500007, Andhra Pradesh, India

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2015年 / 13卷 / 37期

关键词：

C-C BOND; ACTIVATION; CHEMISTRY; OXIDATION; METHYL; ALCOHOLS; SYSTEM;

D O I：

10.1039/c5ob01569c

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel copper-catalyzed aerobic oxidative C(NOH)-C(alkyl) bond cleavage reaction of aryl/aralkyl/vinyl ketones for the synthesis of aromatic/acrylic acids is described. A series of ketones having aryl/aralkyl/vinyl at the one end and methyl to any higher alkyl at the other end can be selectively cleaved and converted into the corresponding acids via oxime intermediates.

引用

页码：9681 / 9685

页数：5

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