Five new chromones possessing monoamine oxidase inhibitory activity from an Ascomycete, Chaetomium quadrangulatum

被引：43

作者：

Fujimoto, H ^{[1
]}

Nozawa, M ^{[1
]}

Okuyama, E ^{[1
]}

Ishibashi, M ^{[1
]}

机构：

[1] Chiba Univ, Grad Sch Pharmaceut Sci, Inage Ku, Chiba 2638522, Japan

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2002年 / 50卷 / 03期

关键词：

Chaetomium quadrangulatum; chromone; monoamine oxidase (MAO) inhibitory activity; chaetoquadrin; fungal metabolite; Ascomycete;

D O I：

10.1248/cpb.50.330

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Five novel chromones (1,4-benzopyran-4-ones), among which three are tetracyclic and one contains a sulfonyl group, have been isolated from an Ascomycete, Chaetomium quadrangulatum, as monoamine oxidase inhibitory features, and named chaetoquadrins A (1)-E (5).

引用

页码：330 / 336

页数：7

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