Extragonadal germ cell tumor of the prostate associated with Klinefelter's syndrome

被引：25

作者：

Namiki, K

Tsuchiya, A

Noda, K

Oyama, H

Ishibashi, K

Kusama, H

Furusato, M

机构：

[1] Tokyo Med Univ, Dept Urol, Shinjuku Ku, Tokyo 1600023, Japan

[2] Tokyo Med Univ, Kasumigaura Hosp, Dept Urol, Inashiki, Ibaraki, Japan

[3] Tokyo Med Univ, Kasumigaura Hosp, Dept Pathol, Inashiki, Ibaraki, Japan

[4] Kyorin Univ, Dept Pathol, Tokyo, Japan

来源：

INTERNATIONAL JOURNAL OF UROLOGY | 1999年 / 6卷 / 03期

关键词：

combined chemotherapy; extragonadal germ cell tumor; Klinefelter's syndrome; prostate neoplasm;

D O I：

10.1046/j.1442-2042.1999.06314.x

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Purpose: We report on a case of extragonadal germ cell tumor of the prostate associated with Klinefelter's syndrome. Methods/Results: The patient was a 33-year-old man. A transrectal prostate biopsy suggested combined germ cell tumor (yolk sac tumor + teratoma). Because there was no tumor except from the prostate, we considered this case to be a primary extragonadal germ cell tumor of the prostate. The prostate tumor responded to systemic chemotherapy with cisplatin, vinblastine and bleomycin and elevated lactate dehydrogenase and alpha-fetoprotein levels normalized. In addition to chemotherapy, the patient also underwent radiation therapy. Conclusion: The patient has survived for approximately 4 years since the diagnosis.

引用

页码：158 / 161

页数：4

共 20 条

[1] CARCINOMA OF PROSTATE IN SEX CHROMATIN POSITIVE (XXX/XY) KLINEFELTERS SYNDROME [J].