Characteristics of laboratory indexes in COVID-19 patients with non-severe symptoms in Hefei City, China: diagnostic value in organ injuries

被引:28
作者
Li, Tao [1 ,2 ]
Wang, Lianzi [1 ]
Wang, Huihui [1 ]
Gao, Yufeng [3 ]
Hu, Xianwei [4 ]
Li, Xuemei [1 ]
Zhang, Shubing [1 ]
Xu, Yuanhong [1 ]
Wei, Wei [2 ]
机构
[1] Anhui Med Univ, Dept Clin Lab, Affiliated Hosp 1, 218 Jixi Rd, Hefei 230032, Anhui, Peoples R China
[2] Anhui Med Univ, Key Lab Antiinflammatory & Immune Med, Minist Educ,Anhui Antiinflammatory & Immune Med I, Inst Clin Pharmacol,Anhui Collaborat Innovat Ctr, 81 Meishan Rd, Hefei 230032, Anhui, Peoples R China
[3] Anhui Med Univ, Dept Infect Dis, Affiliated Hosp 1, Hefei 230032, Peoples R China
[4] Anhui Med Univ, Dept Resp & Crit Care Med, Affiliated Hosp 1, Hefei 230032, Peoples R China
关键词
SARS-CoV-2; COVID-19; Organ injury; Laboratory index; Diagnostic value;
D O I
10.1007/s10096-020-03967-9
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
This study compared the laboratory indexes in 40 non-severe COVID-19 patients with those in 57 healthy controls. In the peripheral blood system of non-severe symptom COVID-19 patients, lymphocytes, eosinophils, basophils, total procollagen type 1 amino-terminal propeptide, osteocalcin N-terminal, thyroid-stimulating hormone, growth hormone, and insulin-like growth factor-binding protein 3 significantly decreased, and total protein, albumin, alanine transaminase, alkaline phosphatase, gamma-glutamyl transferase, activated partial thromboplastin time, prothrombin time, fibrinogen, D-dimer, fibrinogen degradation products, human epididymal protein 4, serum ferritin, and C-reactive protein were elevated. SARS-CoV-2 infection can affect hematopoiesis, hemostasis, coagulation, fibrinolysis, bone metabolism, thyroid, parathyroid glands, the liver, and the reproductive system.
引用
收藏
页码:2447 / 2455
页数:9
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