T Cell Immunity to Varicella-Zoster Virus in the Setting of Advanced HIV and Multiple Varicella-Zoster Virus Recurrences

被引：6

作者：

Ignacio, Rachel A. Bender ^{[1
,2
]}

Ramchandani, Meena S. ^{[1
]}

Laing, Kerry J. ^{[1
]}

Johnston, Christine M. ^{[1
,2
]}

Koelle, David M. ^{[1
,2
,3
]}

机构：

[1] Univ Washington, Dept Med, Div Allergy & Infect Dis, Seattle, WA USA

[2] Fred Hutchinson Canc Res Ctr, Vaccine & Infect Dis Div, 1124 Columbia St, Seattle, WA 98104 USA

[3] Benaroya Res Inst, Seattle, WA USA

来源：

VIRAL IMMUNOLOGY | 2017年 / 30卷 / 01期

基金：

美国国家卫生研究院;

关键词：

varicella-zoster virus; cellular immunology; HIV; herpes zoster; VZV vasculitis; CD4; response; HERPES-ZOSTER; ANTIRETROVIRAL THERAPY; PROPHYLAXIS; ACYCLOVIR; VACCINATION; RESPONSES; EFFICACY; DISEASE; BREADTH; ADULTS;

D O I：

10.1089/vim.2016.0097

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A woman presented with at least four manifestations of varicella-zoster virus (VZV) infection, including central nervous system vasculitis, during her first 2 years of HIV infection. We evaluated her CD4 T cell responses to VZV given the infrequency with which multiple recurrences of VZV occurred, especially following immune reconstitution on antiretroviral therapy.

引用

页码：77 / 80

页数：4

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