T Cell Immunity to Varicella-Zoster Virus in the Setting of Advanced HIV and Multiple Varicella-Zoster Virus Recurrences

被引:6
|
作者
Ignacio, Rachel A. Bender [1 ,2 ]
Ramchandani, Meena S. [1 ]
Laing, Kerry J. [1 ]
Johnston, Christine M. [1 ,2 ]
Koelle, David M. [1 ,2 ,3 ]
机构
[1] Univ Washington, Dept Med, Div Allergy & Infect Dis, Seattle, WA USA
[2] Fred Hutchinson Canc Res Ctr, Vaccine & Infect Dis Div, 1124 Columbia St, Seattle, WA 98104 USA
[3] Benaroya Res Inst, Seattle, WA USA
基金
美国国家卫生研究院;
关键词
varicella-zoster virus; cellular immunology; HIV; herpes zoster; VZV vasculitis; CD4; response; HERPES-ZOSTER; ANTIRETROVIRAL THERAPY; PROPHYLAXIS; ACYCLOVIR; VACCINATION; RESPONSES; EFFICACY; DISEASE; BREADTH; ADULTS;
D O I
10.1089/vim.2016.0097
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
A woman presented with at least four manifestations of varicella-zoster virus (VZV) infection, including central nervous system vasculitis, during her first 2 years of HIV infection. We evaluated her CD4 T cell responses to VZV given the infrequency with which multiple recurrences of VZV occurred, especially following immune reconstitution on antiretroviral therapy.
引用
收藏
页码:77 / 80
页数:4
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