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T Cell Immunity to Varicella-Zoster Virus in the Setting of Advanced HIV and Multiple Varicella-Zoster Virus Recurrences
被引:6
|作者:
Ignacio, Rachel A. Bender
[1
,2
]
Ramchandani, Meena S.
[1
]
Laing, Kerry J.
[1
]
Johnston, Christine M.
[1
,2
]
Koelle, David M.
[1
,2
,3
]
机构:
[1] Univ Washington, Dept Med, Div Allergy & Infect Dis, Seattle, WA USA
[2] Fred Hutchinson Canc Res Ctr, Vaccine & Infect Dis Div, 1124 Columbia St, Seattle, WA 98104 USA
[3] Benaroya Res Inst, Seattle, WA USA
基金:
美国国家卫生研究院;
关键词:
varicella-zoster virus;
cellular immunology;
HIV;
herpes zoster;
VZV vasculitis;
CD4;
response;
HERPES-ZOSTER;
ANTIRETROVIRAL THERAPY;
PROPHYLAXIS;
ACYCLOVIR;
VACCINATION;
RESPONSES;
EFFICACY;
DISEASE;
BREADTH;
ADULTS;
D O I:
10.1089/vim.2016.0097
中图分类号:
R392 [医学免疫学];
Q939.91 [免疫学];
学科分类号:
100102 ;
摘要:
A woman presented with at least four manifestations of varicella-zoster virus (VZV) infection, including central nervous system vasculitis, during her first 2 years of HIV infection. We evaluated her CD4 T cell responses to VZV given the infrequency with which multiple recurrences of VZV occurred, especially following immune reconstitution on antiretroviral therapy.
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页码:77 / 80
页数:4
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