Inverted ILM-flap techniques variants for macular hole surgery: randomized clinical trial to compare retinal sensitivity and fixation stability

被引:19
作者
Cacciamani, Andrea [1 ]
Gelso, Aldo [2 ]
Di Nicola, Marta [3 ,4 ]
Scarinci, Fabio [1 ]
Ripandelli, Guido [1 ]
Costagliola, Ciro [5 ]
Rossi, Tommaso [6 ]
机构
[1] IRCCS Fdn Bietti, Via Livenza 3, I-00198 Rome, Italy
[2] Villa Dei Fiori, Naples, Italy
[3] G DAnnunzio Univ Chieti Pescara, Dept Med Oral & Biotechnol Sci, Chieti, Italy
[4] G DAnnunzio Univ Chieti Pescara, Sch Hyg & Prevent Med, Dept Med & Sci Ageing, Chieti, Italy
[5] Univ Molise, Dept Med & Hlth Sci Vincenzo Tiberio, Campobasso, Italy
[6] IRCCS Osped Policlin San Martino, Genoa, Italy
关键词
LIMITING MEMBRANE FLAP; PATTERNS;
D O I
10.1038/s41598-020-72774-1
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
To report closure rate, Best Corrected Visual Acuity (BCVA), Retinal Sensitivity (RS) and Fixation Stability (FS) of idiopathic Macular Holes (MH) randomized to Cover Group (CG) or Fill Group (FG) of the Inverted Internal Limiting Membrane (ILM) flap surgical procedure. Twenty-eight patients were randomized (1:1) to receive a vitrectomy with either Cover or Fill ILM flap technique. All patients underwent BCVA, RS and FS assessment at baseline, 1-month and 3-months after surgery. MH closed in all patients. BCVA rose from 20/100 (baseline) to 20/33 (1-month) in both groups, to 20/28 in CG versus 20/33 in FG (3-months) (p < 0.05). The central 4 degrees RS rose from 11.5 and 12 dB to 19 and 19.5 dB (1-month) and to 22 and 20 dB (3-months), respectively, in CG and FG (p < 0.001). The central 10 degrees RS rose from 11 and 15 dB to 22 and 20 dB (1-month) and to 23 and 20 dB (3-months), respectively, in CG and FG (p < 0.001). FS increased significantly more in CG. CG improved significantly more than FG in terms of BCVA, RS and FS. The average MH diameter was relatively small (397 mu m); larger MHs may behave differently.
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页数:7
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