LUPUS NEPHRITIS Ancestry, genetic risk and health disparities

被引：3
|
作者：
Bomback, Andrew S. [1 ]
Gharavi, Ali G. [2 ]
机构：
[1] Columbia Univ Med Ctr, Div Nephrol, New York, NY 10032 USA
[2] Columbia Univ Coll Phys & Surg, Dept Med, Div Nephrol, New York, NY 10032 USA
来源：
NATURE REVIEWS NEPHROLOGY | 2013年 / 9卷 / 12期
关键词：
ERYTHEMATOSUS; POPULATION; TNIP1;
D O I：
10.1038/nrneph.2013.210
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
The disease manifestations and outcomes in lupus nephritis are exceptionally heterogeneous. In particular, some ethnic populations are disproportionately affected by the most severe forms of the disease. A new study exploring NF-kappa B dysregulation and its associated genetic variants might help explain the link between ancestry and outcomes in lupus nephritis.
引用
收藏
页码：699 / 700
页数：2
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