1-(Alkyl/arylthiocarbamoyl)benzotriazoles as stable isothiocyanate equivalents: Synthesis of di- and trisubstituted thioureas

被引：61

作者：

Katritzky, AR ^{[1
]}

Ledoux, S ^{[1
]}

Witek, RM ^{[1
]}

Nair, SK ^{[1
]}

机构：

[1] Univ Florida, Dept Chem, Ctr Heterocycl Cmpd, Gainesville, FL 32611 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2004年 / 69卷 / 09期

关键词：

D O I：

10.1021/jo035680d

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1-(Alkyl/arylthiocarbamoyl)benzotriazoles 4a-i were synthesized in yields of 91-99% from bis(benzotriazolyl)methanethione (3). Reagents 4a-g were then used as isothiocyanate equivalents for the efficient synthesis of 10 secondary and 14 tertiary thioureas in high-yielding, convenient processes.

引用

页码：2976 / 2982

页数：7

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