Double stimulus-induced stem cell aggregation during differentiation on a biopolymer hydrogel substrate

被引：28
作者：
Tan, Huaping [1 ]
Gao, Xin [1 ]
Sun, Jinchen [1 ]
Xiao, Chao [1 ]
Hu, Xiaohong [2 ]
机构：
[1] Nanjing Univ Sci & Technol, Sch Mat Sci & Engn, Nanjing 210094, Jiangsu, Peoples R China
[2] Jinling Inst Technol, Sch Mat Engn, Nanjing 211169, Jiangsu, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 98期
基金：
中国国家自然科学基金;
关键词：
LACTOSE-MODIFIED CHITOSAN; CHONDROCYTIC DIFFERENTIATION; INDUCIBLE RELEASE; MAGNETIC FORCE; BIOPHARMACEUTICALS; CHONDROGENESIS;
D O I：
10.1039/c3cc47101b
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A double stimulus-sensing platform based on a biopolymer hydrogel was developed for inducing stem cell aggregation and subsequent release. Our work will bring up a novel methodology to generate smart scaffolds with tailorable properties for biomedical applications.
引用
收藏
页码：11554 / 11556
页数：3
相关论文
共 23 条
  • [1] Construction of Cardiac Tissue Rings Using a Magnetic Tissue Fabrication Technique
    Akiyama, Hirokazu
    Ito, Akira
    Sato, Masanori
    Kawabe, Yoshinori
    Kamihira, Masamichi
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2010, 11 (08): : 2910 - 2920
  • [2] Stimuli-responsive hydrogels - Drugs take control
    Alexander, Cameron
    [J]. NATURE MATERIALS, 2008, 7 (10) : 767 - 768
  • [3] Chondrogenic differentiation of adipose-derived adult stem cells in agarose, alginate, and gelatin scaffolds
    Awad, HA
    Wickham, MQ
    Leddy, HA
    Gimble, JM
    Guilak, F
    [J]. BIOMATERIALS, 2004, 25 (16) : 3211 - 3222
  • [4] Chondrocytic differentiation of human adipose-derived adult stem cells in elastin-like polypeptide
    Betre, H
    Ong, SR
    Guilak, F
    Chilkoti, A
    Fermor, B
    Setton, LA
    [J]. BIOMATERIALS, 2006, 27 (01) : 91 - 99
  • [5] The effects of BMP6 overexpression on adipose stem cell chondrogenesis: Interactions with dexamethasone and exogenous growth factors
    Diekman, Brian O.
    Estes, Bradley T.
    Guilak, Farshid
    [J]. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2010, 93A (03) : 994 - 1003
  • [6] The aggregation of pig articular chondrocyte and synthesis of extracellular matrix by a lactose-modified chitosan
    Donati, I
    Stredanska, S
    Silvestrini, G
    Vetere, A
    Marcon, P
    Marsich, E
    Mozetic, P
    Gamini, A
    Paoletti, S
    Vittur, F
    [J]. BIOMATERIALS, 2005, 26 (09) : 987 - 998
  • [7] Drug-sensing hydrogels for the inducible release of biopharmaceuticals
    Ehrbar, Martin
    Schoenmakers, Ronald
    Christen, Erik H.
    Fussenegger, Martin
    Weber, Wilfried
    [J]. NATURE MATERIALS, 2008, 7 (10) : 800 - 804
  • [8] Potent induction of chondrocytic differentiation of human adipose-derived adult stem cells by bone morphogenetic protein 6
    Estes, BT
    Wu, AW
    Guilak, F
    [J]. ARTHRITIS AND RHEUMATISM, 2006, 54 (04): : 1222 - 1232
  • [9] Use of Magnetic Forces to Promote Stem Cell Aggregation During Differentiation, and Cartilage Tissue Modeling
    Fayol, D.
    Frasca, G.
    Le Visage, C.
    Gazeau, F.
    Luciani, N.
    Wilhelm, C.
    [J]. ADVANCED MATERIALS, 2013, 25 (18) : 2611 - 2616
  • [10] FGF-2 abolishes the chondrogenic effect of combined BMP-6 and TGF-β in human adipose derived stem cells
    Hildner, Florian
    Peterbauer, Anja
    Wolbank, Susanne
    Nuernberger, Sylvia
    Marlovits, Stefan
    Redl, Heinz
    van Griensven, Martijn
    Gabriel, Christian
    [J]. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2010, 94A (03) : 978 - 987
123