Diffuse traumatic brain injury and the sensory brain

被引：23
|
作者：
Alwis, Dasuni S. [1 ]
Johnstone, Victoria [1 ]
Yan, Edwin [1 ]
Rajan, Ramesh [1 ]
机构：
[1] Monash Univ, Dept Physiol, Melbourne, Vic 3800, Australia
来源：
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY | 2013年 / 40卷 / 07期
基金：
英国医学研究理事会;
关键词：
brain injury; diffuse axonal injury; sensory cortex; traumatic behaviour deficit; CONTROLLED CORTICAL IMPACT; VISUAL PROCESSING DEFICITS; FLUID-PERCUSSION INJURY; LONG-TERM POTENTIATION; AXONAL INJURY; LIPID-PEROXIDATION; OXIDATIVE STRESS; CONTUSION TRAUMA; RECEPTIVE-FIELD; RODENT WHISKING;
D O I：
10.1111/1440-1681.12100
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
In this review we discuss the consequences to the brain's cortex, specifically to the sensory cortex, of traumatic brain injury. The thesis underlying this approach is that long-term deficits in cognition seen after brain damage in humans are likely underpinned by an impaired cortical processing of the sensory information needed to drive cognition or to be used by cognitive processes to produce a response. We take it here that the impairment to sensory processing does not arise from damage to peripheral sensory systems, but from disordered brain processing of sensory input.
引用
收藏
页码：473 / 483
页数：11
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