Genetics of pancreatic cancer and implications for therapy

被引：11

作者：

Bhosale, Priya ^{[1
]}

Cox, Veronica ^{[1
]}

Faria, Silvana ^{[1
]}

Javadi, Sanaz ^{[1
]}

Viswanathan, Chitra ^{[1
]}

Koay, Eugene ^{[2
]}

Tamm, Eric ^{[1
]}

机构：

[1] Univ Texas MD Anderson Canc Ctr, Dept Diagnost Radiol, Unit 38,1515 Holcombe Blvd, Houston, TX 77030 USA

[2] Univ Texas MD Anderson Canc Ctr, Dept Radiat Oncol, Houston, TX 77030 USA

来源：

ABDOMINAL RADIOLOGY | 2018年 / 43卷 / 02期

基金：

美国国家卫生研究院;

关键词：

Pancreatic cancer; Genomics; Imaging Mutations; HEREDITARY PANCREATITIS; INTRAEPITHELIAL NEOPLASIA; BRCA MUTATION; CLINICAL CHARACTERISTICS; SOMATIC MUTATIONS; FAMILY-HISTORY; RISK-FACTORS; PHASE-II; ADENOCARCINOMA; GEMCITABINE;

D O I：

10.1007/s00261-017-1394-y

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Pancreatic cancer is a highly lethal disease with a dismal 5-year prognosis. Knowledge of its genetics may help in identifying new methods for patient screening, and cancer treatment. In this review, we will describe the most common mutations responsible for the genesis of pancreatic cancer and their impact on screening, patterns of disease progression, and therapy.

引用

页码：404 / 414

页数：11

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