Gastric Cancer After Helicobacter pylori Eradication for Nodular Gastritis in an Adolescent

被引:2
作者
Okmaura, Takuma [1 ]
Iwaya, Yugo [2 ]
Iwaya, Mai [3 ]
Koizumi, Tomonobu [4 ]
Nagaya, Tadanobu [1 ]
机构
[1] Shinshu Univ, Dept Gastroenterol, Matsumoto, Nagano, Japan
[2] Shinshu Univ, Dept Adv Therapeut Endoscopy, Matsumoto, Nagano, Japan
[3] Shinshu Univ Hosp, Dept Lab Med, Matsumoto, Nagano, Japan
[4] Shinshu Univ, Dept Hematol & Med Oncol, Matsumoto, Nagano, Japan
关键词
nodular gastritis; eradication therapy; gastric cancer; adolescent; helicobacter pylori; DIFFUSE-TYPE; INFECTION;
D O I
10.7759/cureus.29984
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 16-year-old girl underwent esophagogastroduodenoscopy (EGD) after the detection of Helicobacter pylori (H. pylon) antibodies in her urine during a school health screening, which revealed nodular gastritis (NG). She was diagnosed as having H. pylon infection histologically and by biopsy culture specimens and soon commenced eradication therapy. Eight weeks later, eradication was confirmed by a urea breath test. At the age of 19, however, she was referred to our hospital with epigastralgia and lower back pain. EGD revealed ulcerative lesions with enlarged folds at the greater curvature of the gastric body. Biopsy specimens of the lesions revealed poorly differentiated adenocarcinoma and signet ring cell carcinoma. The cancer was classified as stage IV with pancreatic invasion. Although NG with pangastritis is considered a high-risk factor for diffuse-type gastric carcinoma, the course of NG after eradication remains unknown. Careful histological assessment before eradication by endoscopic biopsy and close follow-up after eradication are therefore recommended, even in young patients.
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页数:6
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