Diagnostic and Pathophysiological Impact of Myocardial MIBG Scintigraphy in Parkinson's Disease

被引：16
作者：
Spiegel, Joerg [1 ]
机构：
[1] Univ Saarland, Dept Neurol, D-66421 Homburg, Germany
来源：
PARKINSONS DISEASE | 2010年 / 2010卷
关键词：
CARDIAC SYMPATHETIC DENERVATION; I-123-MIBG SCINTIGRAPHY; LEWY BODIES; DIFFERENTIAL-DIAGNOSIS; CLINICAL-DIAGNOSIS; METAIODOBENZYLGUANIDINE; DEGENERATION; DYSFUNCTION; PHEOCHROMOCYTOMA; ACCURACY;
D O I：
10.4061/2010/295346
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Myocardial MIBG scintigraphy is established in the diagnosis and differential diagnosis of Parkinson's disease (PD). Numerous studies address the pathophysiological impact of myocardial MIBG scintigraphy: the myocardial MIBG uptake correlates with the clinical phenotype of PD; the background of this phenomenon is unclear. Furthermore MIBG scintigraphy enables to study the extracranial Lewy body type-degeneration. In combination with cerebral dopamine transporter imaging, MIBG scintigraphy allows to correlate cerebral and extracranial Lewy body type-degeneration in PD.
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页数：6
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共 53 条
  • [41] Sisson JC, 1999, Q J NUCL MED, V43, P217
  • [42] A PHARMACOLOGICAL GUIDE TO MEDICINES WHICH INTERFERE WITH THE BIODISTRIBUTION OF RADIOLABELED METAIODOBENZYLGUANIDINE (METAIODOBENZYLGUANIDINE)
    SOLANKI, KK
    BOMANJI, J
    MOYES, J
    MATHER, SJ
    TRAINER, PJ
    BRITTON, KE
    [J]. NUCLEAR MEDICINE COMMUNICATIONS, 1992, 13 (07) : 513 - 521
  • [43] FP-CIT and MIBG scintigraphy in early Parkinson's disease
    Spiegel, J
    Möllers, MO
    Jost, WH
    Fuss, G
    Samnick, S
    Dillmann, U
    Becker, G
    Kirsch, CM
    [J]. MOVEMENT DISORDERS, 2005, 20 (05) : 552 - 561
  • [44] Myocardial sympathetic degeneration correlates with clinical phenotype of Parkinson's disease
    Spiegel, Joerg
    Hellwig, Dirk
    Farmakis, Georgios
    Jost, Wolfgang H.
    Samnick, Samuel
    Fassbender, Klaus
    Kirsch, Carl-Martin
    Dillmann, Ulrich
    [J]. MOVEMENT DISORDERS, 2007, 22 (07) : 1004 - 1008
  • [45] Spiegel Jorg, 2007, Open Neurol J, V1, P1, DOI 10.2174/1874205X00701010001
  • [46] Impaired myocardial 123I-metaiodobenzylguanidine uptake in Lewy body disease:: Comparison between dementia with Lewy bodies and Parkinson's disease
    Suzuki, M
    Kuriita, A
    Hashimoto, M
    Fukumitsu, N
    Abo, M
    Ito, Y
    Urashima, M
    Inoue, K
    [J]. JOURNAL OF THE NEUROLOGICAL SCIENCES, 2006, 240 (1-2) : 15 - 19
  • [47] Cardiac sympathetic denervation in bradykinesia-dominant Parkinson's disease
    Suzuki, Masahiko
    Urashima, Mitsuyoshi
    Oka, Hisayoshi
    Hashimoto, Masaya
    Taira, Kenichiro
    [J]. NEUROREPORT, 2007, 18 (17) : 1867 - 1870
  • [48] Peripheral sympathetic dysfunction in patients with Parkinson's disease without autonomic failure is heart selective and disease specific
    Taki, J
    Nakajima, K
    Hwang, EH
    Matsunari, I
    Komai, K
    Yoshita, M
    Sakajiri, K
    Tonami, N
    [J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE, 2000, 27 (05) : 566 - 573
  • [49] WIELAND DM, 1980, J NUCL MED, V21, P349
  • [50] Quantitative scintigraphic analysis of I-123-MIBG by polar map in patients with dilated cardiomyopathy
    Yamazaki, J
    Muto, H
    Ishiguro, S
    Okamoto, K
    Hosoi, H
    Nakano, H
    Morishita, T
    [J]. NUCLEAR MEDICINE COMMUNICATIONS, 1997, 18 (03) : 219 - 229
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