Secreted IL-12p70 from long-term activated dendritic cells is lost concomitant with their apoptosis and release of IL-10

被引:0
|
作者
Hansen, Morten
Carstensen, Laura Stentoft
Obers, Andreas
Svane, Inge Marie Stentoft
机构
[1] Natl Ctr Canc Immune Therapy, Herlev, Denmark
[2] Univ Copenhagen, Herlev, Denmark
[3] Herlev Univ Hosp, Ctr Canc Immune Therapy, Herlev, Denmark
关键词
D O I
10.1158/2326-6074.CRICIMTEATIAACR18-A079
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
A079
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Effect of endogenously produced IL-10 on secretion of IL-12p70 by interferon-alpha dendritic cells
    Kharazi, A
    Kudinov, Y
    Wiseman, C
    JOURNAL OF IMMUNOTHERAPY, 2004, 27 (06) : S24 - S25
  • [2] Human Herpesvirus 6B Induces Phenotypic Maturation Without IL-10 and IL-12p70 Production in Dendritic Cells
    Bertelsen, L. B.
    Petersen, C. C.
    Kofod-Olsen, E.
    Oster, B.
    Hollsberg, P.
    Agger, R.
    Hokland, M.
    SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2010, 71 (06) : 431 - 439
  • [3] Human breast tumor cells express IL-10 and IL-12p40 transcripts and proteins, but do not produce IL-12p70
    Heckel, Mark C.
    Wolfson, Alexey
    Slachta, Christopher A.
    Schwarting, Roland
    Salgame, Padmini
    Katsetos, Christos D.
    Platsoucas, Chris D.
    CELLULAR IMMUNOLOGY, 2011, 266 (02) : 143 - 153
  • [4] IL10 and IL12B polymorphisms each influence IL-12p70 secretion by dendritic cells in response to LPS
    Peng, JC
    Abu Bakar, S
    Richardson, MM
    Jonsson, JJ
    Frazer, IH
    Nielsen, LK
    Morahan, G
    Thomas, R
    IMMUNOLOGY AND CELL BIOLOGY, 2006, 84 (02): : 227 - 232
  • [5] Deficient IL-12p70 secretion by dendritic cells based on IL12B promoter genotype
    Müller-Berghaus, J
    Kern, K
    Paschen, A
    Nguyen, XD
    Klüter, H
    Morahan, G
    Schadendorf, D
    GENES AND IMMUNITY, 2004, 5 (05) : 431 - 434
  • [6] Deficient IL-12p70 secretion by dendritic cells based on IL12B promoter genotype
    J Müller-Berghaus
    K Kern
    A Paschen
    X D Nguyen
    H Klüter
    G Morahan
    D Schadendorf
    Genes & Immunity, 2004, 5 : 431 - 434
  • [7] Dendritic cells are able to produce IL-12p70 after uptake of apoptotic cells
    Johansson, Ulrika
    Walther-Jallow, Lilian
    Hofmann, Anette
    Spetz, Anna-Lena
    IMMUNOBIOLOGY, 2011, 216 (1-2) : 251 - 255
  • [8] Development of a potency assay for human dendritic cells: IL-12P70 production
    Butterfield, Lisa H.
    Gooding, William E.
    Whiteside, Theresa L.
    JOURNAL OF IMMUNOTHERAPY, 2007, 30 (08) : 904 - 904
  • [9] Development of a potency assay for human dendritic cells: IL-12p70 production
    Butterfield, Lisa H.
    Gooding, William
    Whiteside, Theresa L.
    JOURNAL OF IMMUNOTHERAPY, 2008, 31 (01) : 89 - 100