ADAPted secretion of cytokines in NK cells

被引：15
|
作者：
Vivier, Eric [1 ,2 ,3 ,4 ]
Ugolini, Sophie [1 ,2 ,3 ]
Nunes, Jacques A. [5 ,6 ,7 ,8 ]
机构：
[1] Ctr Immunol Marseille Luminy, INSERM, U1104, Marseille, France
[2] CNRS, UMR7280, Marseille, France
[3] Aix Marseille Univ, UM2, Marseille, France
[4] Hop Conception, AP HP, Serv Immunol, Marseille, France
[5] Ctr Rech Cancerol Marseille, INSERM, U1068, Marseille, France
[6] CNRS, UMR7258, Marseille, France
[7] Aix Marseille Univ, UM105, Marseille, France
[8] Inst J Paoli I Calmettes, F-13009 Marseille, France
来源：
NATURE IMMUNOLOGY | 2013年 / 14卷 / 11期
关键词：
NATURAL-KILLER-CELLS; NF-KAPPA-B; SIGNALING PATHWAYS; MEDIATED CYTOTOXICITY; T-CELLS; PROTEINS; ACTIVATION; CARMA1; KINASE;
D O I：
10.1038/ni.2737
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
A signaling module consisting of the adaptor ADAP and the Carma1-Bcl-10-MALT1 (CBM)-TAK1 signalosome has been shown to selectively induce cytokine secretion but not cytotoxicity in natural killer cells.
引用
收藏
页码：1108 / 1110
页数：3
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