Successful recovery of COVID-19-associated recurrent diarrhea and gastrointestinal hemorrhage using convalescent plasma

被引：7
作者：
Zhang, Li-Bo [1 ,2 ]
Pang, Rong-Rong [1 ,2 ]
Qiao, Qing-Hua [3 ,4 ]
Wang, Zhi-Hua [4 ,5 ,6 ]
Xia, Xin-Yi [1 ,4 ,6 ]
Wang, Chang-Jun [6 ,7 ]
Xu, Xiao-Li [6 ,8 ]
机构：
[1] Southern Med Univ, Sch Clin Med 1, Sch Med, COVID 19 Res Ctr,Inst Lab Med,Jinling Hosp, Nanjing 210002, Jiangsu, Peoples R China
[2] Nanjing Red Cross Blood Ctr, Dept Lab Med, Nanjing 210003, Jiangsu, Peoples R China
[3] 989th Hosp, Med & Tech Support Dept, Pingdingshan 467000, Henan, Peoples R China
[4] Wuhan Huoshenshan Hosp, Dept Lab Med & Blood Transfus, Wuhan 430100, Hubei, Peoples R China
[5] 907th Hosp, Dept Lab Med & Blood Transfus, Nanping 350702, Fujian, Peoples R China
[6] Wuhan Huoshenshan Hosp, Joint Expert Grp COVID 19, Wuhan 430100, Hubei, Peoples R China
[7] Ctr Dis Control & Prevent PLA, 20 Dongda St, Beijing 100071, Peoples R China
[8] Nanjing Univ, Jinling Hosp, Sch Med, Dept Med Adm, 305 East Zhongshan Rd, Nanjing 210002, Jiangsu, Peoples R China
来源：
MILITARY MEDICAL RESEARCH | 2020年 / 7卷 / 01期
关键词：
Coronavirus disease 2019 (COVID-19); Convalescent plasma; SARS-CoV-2; virus; Gastrointestinal symptoms; COVID-19;
D O I：
10.1186/s40779-020-00273-5
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Background Gastrointestinal symptoms are not rare among coronavirus disease 2019 (COVID-19) patients, but there have been no reports regarding convalescent plasma therapy for the recovery of gastrointestinal problems in COVID-19 patients. Case presentation We present two cases of patients with COVID-19-associated recurrent diarrhea and positive fecal occult blood who successfully recovered after a one-time convalescent plasma administration. Conclusion When COVID-19 patients develop recurrent or refractory gastrointestinal symptoms and fail to respond to the available treatment, alternative therapy with convalescent plasma administration may be considered.
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页数：6
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