Stabilization of silver nanoparticles in chitosan and gelatin hydrogel and its applications

被引：45

作者：

Nghi Thi-Phuong Nguyen ^{[1
]}

Long Vuong-Hoang Nguyen ^{[1
]}

Nhi Tra Thanh ^{[1
]}

Vo Van Toi ^{[1
]}

Tran Ngoc Quyen ^{[2
,3
]}

Tran, Phong A. ^{[4
]}

Wang, Hui-Min David ^{[5
,6
,7
,8
]}

Thi-Hiep Nguyen ^{[1
]}

机构：

[1] Vietnam Natl Univ Ho Chi Minh City VNU HCM, Int Univ, Dept Biomed Engn, Hcmc 700000, Vietnam

[2] Vietnam Acad Sci & Technol, Grad Sch Sci & Technol Viet Nam, Hochiminh City 700000, Vietnam

[3] Vietnam Acad Sci & Technol, Inst Appl Mat Sci, Hochiminh City 700000, Vietnam

[4] QUT, Brisbane, Qld, Australia

[5] Natl Chung Hsing Univ, Grad Inst Biomed Engn, Taichung 402, Taiwan

[6] China Med Univ, Dept Med Lab Sci & Biotechnol, Taichung 404, Taiwan

[7] Quanzhou Normal Univ, Coll Oceanol & Food Sci, Quanzhou 362000, Peoples R China

[8] Kaohsiung Med Univ, Grad Inst Med, Coll Med, Kaohsiung 807, Taiwan

来源：

MATERIALS LETTERS | 2019年 / 248卷

关键词：

Chitosan; Gelatin; Electrospinning; Silver nanoparticles;

D O I：

10.1016/j.matlet.2019.03.103

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

This study aims to investigate the effect of chitosan and gelatin as a stabilizer of silver nanoparticles (Ag NPs) and on their application designs. Ag NPs hydrogels was synthesized and stabilized by capping agents (chitosan and gelatin). Then, Ag NPs membrane was prepared by coating Ag NPs hydrogel on PCL fibrils. Optical and microscopic observation as well as structural properties were studied to compare two stabilizers. Antimicrobial testing was done on both Ag NPs hydrogels and membranes. The results suggest that gelatin provides better stabilizing activity and superior antimicrobial potency in membrane form while chitosan exhibits better antibacterial inhibition in hydrogel form. (C) 2019 Published by Elsevier B.V.

引用

页码：241 / 245

页数：5

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