Budd-Chiari syndrome associated with hypereosinophilic syndrome; A case report

被引：19

作者：

Inoue, Ai ^{[1
]}

Michitaka, Kojiro ^{[1
]}

Shigematsu, Shuichiro ^{[1
,2
]}

Konishi, Ichiro ^{[1
]}

Hirooka, Masashi ^{[1
]}

Hiasa, Yoichi ^{[1
]}

Matsui, Hidetaka ^{[1
]}

Matsuura, Bunzo ^{[1
]}

Horiike, Norio ^{[1
]}

Hato, Takaaki ^{[3
]}

Miyaoka, Hiroaki ^{[2
]}

Onji, Morikazu ^{[1
]}

机构：

[1] Ehime Univ, Grad Sch Med, Dept Gastroenterol & Metabol, Toon City, Japan

[2] Saiseikai Matsuyama Hosp, Matsuyama, Ehime, Japan

[3] Ehime Univ, Grad Sch Med, Dept Bioregulatory Med, Toon City, Japan

来源：

INTERNAL MEDICINE | 2007年 / 46卷 / 14期

关键词：

Budd-Chiari syndrome; hypereosinophilic syndrome; FIP1 like 1 (FIP1L1) gene; platelet-derived growth factor receptor alpha (PDGFRA) genes; obstructive thrombophlebitis;

D O I：

10.2169/internalmedicine.46.6438

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 27-year-old man was admitted due to abdominal fullness. He had ascites and subcutaneous nodules on his head, with liver dysfunction and eosinophilia. Abdominal imaging revealed obstruction of the hepatic veins and stenosis of the inferior vena cava. Histological diagnosis of a subcutaneous nodule revealed obstructive thrombophlebitis with eosinophils. Tyrosine kinase created by fusion of the FIP1L1 and PDGFRA genes, which is characteristic of hypereosinophilic syndrome (HES), was detected. He was diagnosed with Budd-Chiari syndrome associated with HES. Liver function tests improved after interventional therapy followed by steroid therapy. It is important to diagnose the cause of Budd-Chiari syndrome.

引用

页码：1095 / 1100

页数：6

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