Synthesis of (-)-histrionicotoxin by a tandem process

被引：94

作者：

Williams, GM

Roughley, SD

Davies, JE

Holmes, AB

Adams, JP

机构：

[1] Univ Cambridge, Dept Chem, Chem Lab, Cambridge CB2 1EW, England

[2] Glaxo Wellcome Res & Dev Ltd, Med Res Ctr, Stevenage SG1 2NY, Herts, England

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1999年 / 121卷 / 20期

关键词：

D O I：

10.1021/ja990138l

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：4900 / 4901

页数：2

共 26 条

[1] MODEL STUDIES ON THE ACTIVE-SITE OF CYTOCHROME-P-450 - AN FEII PORPHYRIN CARRYING A STRAPPED THIOLATE LIGAND [J].

BATTERSBY, AR ;

HOWSON, W ;

HAMILTON, AD .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1982, (21) :1266-1268

[2] A TOTAL SYNTHESIS OF D,1-HISTRIONICOTOXIN [J].

CAREY, SC ;

ARATANI, M ;

KISHI, Y .

TETRAHEDRON LETTERS, 1985, 26 (48) :5887-5890

[3]

CONGREVE MS, 1993, SYNLETT, P663

[4] Regio- and diastereoselective 1,3-dipolar cycloaddition of imidazoline 3-oxides to styrene [J].

Coskun, N ;

Ay, M .

HETEROCYCLES, 1998, 48 (03) :537-544

[5] HISTRIONICOTOXINS - ROENTGEN-RAY ANALYSIS OF NOVEL ALLENIC AND ACETYLENIC SPIROALKALOIDS ISOLATED FROM A COLOMBIAN FROG, DENDROBATES-HISRIONICUS [J].

DALY, JW ;

KARLE, I ;

MYERS, CW ;

TOKUYAMA, T ;

WATERS, JA ;

WITKOP, B .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1971, 68 (08) :1870-&

[6] N-alkenyl nitrone dipolar cycloaddition routes to piperidines and indolizidines .8. the scope of tandem reactions involving hydroxylamine-alkyne cyclisations [J].

Davison, EC ;

Forbes, IT ;

Holmes, AB ;

Warner, JA .

TETRAHEDRON, 1996, 52 (35) :11601-11624

[7] N-ALKENYL NITRONE DIPOLAR CYCLOADDITION ROUTES TO PIPERIDINES AND INDOLIZIDINES .7. HYDROXYLAMINE ALKYNE CYCLIZATIONS - FORMATION OF CYCLIC NITRONES AND APPLICATION TO THE SYNTHESIS OF THE PROPOSED STRUCTURE FOR (+/-)-ACACIALACTAM [J].

FOX, ME ;

HOLMES, AB ;

FORBES, IT ;

THOMPSON, M .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1994, (23) :3379-3395

[8] PALLADIUM(II)-CATALYZED CASCADE CYCLIZATION CYCLOADDITION REACTIONS OF ALKENYL OXIMES [J].

FREDERICKSON, M ;

GRIGG, R ;

MARKANDU, J ;

REDPATH, J .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1994, (19) :2225-2226

[9] REGIOCONTROLLED AND STEREOCONTROLLED SYNTHESIS OF ALLENIC AND ACETYLENIC DERIVATIVES - ORGANOTITANIUM AND BORON REAGENTS [J].

FURUTA, K ;

ISHIGURO, M ;

HARUTA, R ;

IKEDA, N ;

YAMAMOTO, H .

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1984, 57 (10) :2768-2776

[10] PROBES FOR A REGULATORY SITE ON THE NICOTINIC ACETYLCHOLINE RECEPTOR-CHANNEL - SYNTHESIS OF (+/-)-7-DEBUTYLPERHYDROHISTRIONICOTOXIN, (+--)-2-DEPENTYL-7-DEBUTYLPERHYDROHISTRIONICOTOXIN, AND THEIR ANALOGS [J].

GESSNER, W ;

TAKAHASHI, K ;

WITKOP, B ;

BROSSI, A ;

ALBUQUERQUE, EX .

HELVETICA CHIMICA ACTA, 1985, 68 (01) :49-55

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