Metal-containing and related polymers for biomedical applications

被引：244

作者：

Yan, Yi ^{[1
,2
]}

Zhang, Jiuyang ^{[1
,3
]}

Ren, Lixia ^{[4
]}

Tang, Chuanbing ^{[1
]}

机构：

[1] Univ South Carolina, Dept Chem & Biochem, Columbia, SC 29208 USA

[2] Northwestern Polytech Univ, Sch Sci, Dept Appl Chem, Xian 710129, Shannxi, Peoples R China

[3] Southeast Univ, Sch Chem & Chem Engn, Nanjing 211189, Jiangsu, Peoples R China

[4] Tianjin Univ, Sch Mat Sci & Engn, Tianjin 300072, Peoples R China

来源：

CHEMICAL SOCIETY REVIEWS | 2016年 / 45卷 / 19期

基金：

美国国家科学基金会;

关键词：

MRI CONTRAST AGENTS; RING-OPENING POLYMERIZATION; HETEROBIMETALLIC BLOCK-COPOLYMERS; NANOSCALE COORDINATION POLYMERS; POLYION COMPLEX MICELLES; PHOTODYNAMIC THERAPY; METALLOCENE POLYMERS; BIODEGRADABLE POLYMER; RUTHENIUM-PORPHYRIN; CONTROLLED-RELEASE;

D O I：

10.1039/c6cs00026f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A survey of the most recent progress in the biomedical applications of metal-containing polymers is given. Due to the unique optical, electrochemical, and magnetic properties, at least 30 different metal elements, most of them transition metals, are introduced into polymeric frameworks for interactions with biology-relevant substrates via various means. Inspired by the advance of metal-containing small molecular drugs and promoted by the great progress in polymer chemistry, metal-containing polymers have gained momentum during recent decades. According to their different applications, this review summarizes the following biomedical applications: ( 1) metal-containing polymers as drug delivery vehicles; ( 2) metal-containing polymeric drugs and biocides, including antimicrobial and antiviral agents, anticancer drugs, photodynamic therapy agents, radiotherapy agents and biocides; ( 3) metal-containing polymers as biosensors, and ( 4) metal-containing polymers in bioimaging.

引用

页码：5232 / 5263

页数：32

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