Informed consent for live liver donors: A qualitative, prospective study

被引:12
作者
Gordon, Elisa J. [1 ,2 ]
Rodde, Jillian [1 ]
Skaro, Anton [2 ]
Baker, Talia [2 ]
机构
[1] Northwestern Univ, Feinberg Sch Med, Ctr Healthcare Studies, Chicago, IL 60611 USA
[2] Northwestern Univ, Feinberg Sch Med, Comprehens Transplant Ctr, Chicago, IL 60611 USA
关键词
Bioethics; Liver transplantation; Information needs; Informed consent; Education; Qualitative research; Risk communication; HEALTH ASSESSMENT; DECISION-MAKING; ETHICAL-ISSUES; TRANSPLANTATION; DONATION; OUTCOMES; COMPLICATIONS; EXPECTATIONS; CARE; COMPREHENSION;
D O I
10.1016/j.jhep.2015.05.003
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background & Aims: Adult-to-adult live donor liver transplantation (LDLT) poses serious health risks and no direct health benefits to donors. Ensuring live donors' autonomy through informed consent is critical. We assessed live liver donors' (LD) comprehension, information needs, risk perceptions, and demographics. Methods: Semi-structured interviews were prospectively conducted with LDs after completing donor evaluation and informed consent at our transplant center. Likert scales measured informed consent domains. Open-ended responses underwent thematic analysis. Results: Thirty LDs participated (100% participation rate). Although 90% of LDs reported being informed about donation 'a great deal', only 66% reported understanding information about donation 'a great deal.' Many (40%) reported difficulty understanding medical terminology. Information LDs most desired to feel comfortable with their decision included: incidence and type of donor complications (67%), description of donation procedure (57%), and the process of donor preparation (43%). Most (83%) LDs rated risks to themselves as 'not at all' to 'somewhat' risky, and minimized these risks. Conclusions: Although LDs perceived that they were adequately informed, their actual comprehension about donation was inadequate. Findings suggest the value of informed consent for preparation for the procedure and potential periprocedural risks rather than for decision-making. More comprehensible information disclosure may optimize informed consent. (C) 2015 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:838 / 847
页数:10
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