Association of Interleukin 7 Immunotherapy With Lymphocyte Counts Among Patients With Severe Coronavirus Disease 2019 (COVID-19)

被引:68
作者
Laterre, Pierre Francois [1 ]
Francois, Bruno [2 ,3 ,4 ]
Collienne, Christine [1 ]
Hantson, Philippe [1 ]
Jeannet, Robin [5 ]
Remy, Kenneth E. [6 ,7 ,8 ]
Hotchkiss, Richard S. [7 ,8 ,9 ]
机构
[1] Catholic Univ Louvain, St Luc Univ Hosp, Dept Crit Care Med, Ave Hippocrate 10, B-1200 Brussels, Belgium
[2] Univ Hosp Limoges, Intens Care Unit Dept, Limoges, France
[3] Univ Hosp Limoges, INSERM, Ctr Invest Clin 1435, Limoges, France
[4] Univ Hosp Limoges, Unite Mixte Rech 1092, Limoges, France
[5] Univ Hosp Limoges, Dept Intens Care Med & Anaesthesiol, Limoges, France
[6] Washington Univ, Sch Med, Dept Pediat, St Louis, MO 63110 USA
[7] Washington Univ, Sch Med, Dept Anesthesiol & Crit Care Med, St Louis, MO USA
[8] Washington Univ, Sch Med, Dept Med, St Louis, MO 63110 USA
[9] Washington Univ, Sch Med, Dept Surg, St Louis, MO 63110 USA
关键词
IL-7;
D O I
10.1001/jamanetworkopen.2020.16485
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页数:5
相关论文
共 6 条
  • [1] Flip the coin: IL-7 and IL-7R in health and disease
    Barata, Joao T.
    Durum, Scott K.
    Seddon, Benedict
    [J]. NATURE IMMUNOLOGY, 2019, 20 (12) : 1584 - 1593
  • [2] Interleukin-7 restores lymphocytes in septic shock: the IRIS-7 randomized clinical trial
    Francois, Bruno
    Jeannet, Robin
    Daix, Thomas
    Walton, Andrew H.
    Shotwell, Matthew S.
    Unsinger, Jacqueline
    Monneret, Guillaume
    Rimmele, Thomas
    Blood, Teresa
    Morre, Michel
    Gregoire, Anne
    Mayo, Gail A.
    Blood, Jane
    Durum, Scott K.
    Sherwood, Edward R.
    Hotchkiss, Richard S.
    [J]. JCI INSIGHT, 2018, 3 (05)
  • [3] Harnessing the biology of IL-7 for therapeutic application
    Mackall, Crystal L.
    Fry, Terry J.
    Gress, Ronald E.
    [J]. NATURE REVIEWS IMMUNOLOGY, 2011, 11 (05) : 330 - 342
  • [4] Postmortem examination of COVID-19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings in lungs and other organs suggesting vascular dysfunction
    Menter, Thomas
    Haslbauer, Jasmin D.
    Nienhold, Ronny
    Savic, Spasenija
    Deigendesch, Helmut
    Frank, Stephan
    Turek, Daniel
    Willi, Niels
    Pargger, Hans
    Bassetti, Stefano
    Leuppi, Joerg D.
    Cathomas, Gieri
    Tolnay, Markus
    Mertz, Kirsten D.
    Tzankov, Alexandar
    [J]. HISTOPATHOLOGY, 2020, 77 (02) : 198 - 209
  • [5] The many faces of the anti-COVID immune response
    Vardhana, Santosha A.
    Wolchok, Jedd D.
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 2020, 217 (06)
  • [6] Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China
    Wang, Dawei
    Hu, Bo
    Hu, Chang
    Zhu, Fangfang
    Liu, Xing
    Zhang, Jing
    Wang, Binbin
    Xiang, Hui
    Cheng, Zhenshun
    Xiong, Yong
    Zhao, Yan
    Li, Yirong
    Wang, Xinghuan
    Peng, Zhiyong
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2020, 323 (11): : 1061 - 1069