Bronchial Thermoplasty

被引：7
作者：
Mainardi, Anne S. [1 ]
Castro, Mario [2 ]
Chupp, Geoffrey [1 ]
机构：
[1] Yale Univ, Sch Med, Div Pulm Crit Care & Sleep Med, Dept Internal Med, 300 Cedar St, New Haven, CT 06520 USA
[2] Washington Univ, Sch Med, Div Pulm & Crit Care Med, Dept Internal Med, 4523 Clayton Ave, St Louis, MO 63110 USA
来源：
CLINICS IN CHEST MEDICINE | 2019年 / 40卷 / 01期
关键词：
Bronchial thermoplasty; Radiofrequency ablation; Severe asthma; Airway smooth muscle; AIRWAY SMOOTH-MUSCLE; TARGETED LUNG DENERVATION; SEVERE REFRACTORY ASTHMA; SUBEPITHELIAL FIBROSIS; COST-EFFECTIVENESS; PERSISTENT ASTHMA; DOUBLE-BLIND; TERM SAFETY; INFLAMMATION; MODERATE;
D O I：
10.1016/j.ccm.2018.10.015
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
Bronchial thermoplasty is an advanced therapy for severe asthma. It is a bronchoscopic procedure in which radiofrequency energy is applied to the airway wall, resulting in decreased airway smooth muscle burden. Human trials have shown that bronchial thermoplasty may reduce asthma exacerbations and improve quality of life in patients with severe uncontrolled asthma. It has been demonstrated to be a safe procedure, with most adverse events being early and mild. More studies are required to understand the precise effects of bronchial thermoplasty on the asthmatic airway and optimal parameters to appropriately select patients for this novel procedure.
引用
收藏
页码：193 / +
页数：17
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