Synthesis of N-substituted 4-methylene-3,4-dihydro-1(2H)-isoquinolin-1-ones via a palladium-catalysed three-component process

被引：21

作者：

Grigg, R ^{[1
]}

Khamnaen, T

Rajviroongit, S

Sridharan, V

机构：

[1] Univ Leeds, Sch Chem, MIDAS Ctr, Leeds LS2 9JT, W Yorkshire, England

[2] Mahidol Univ, Fac Sci, Dept Chem, Bangkok 10400, Thailand

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 14期

关键词：

D O I：

10.1016/S0040-4039(02)00329-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel palladium-catalysed three-component cascade process involving 2-iodobenzoyl chloride or methyl 2-iodobenzoate, allene and primary aliphatic or aromatic amines furnishes N-substituted 4-methylene-3,4-dihydro-1 (2H)-isoquinolin-1-ones in good yield. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：2601 / 2603

页数：3

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