TM-MC: a database of medicinal materials and chemical compounds in Northeast Asian traditional medicine

被引:54
作者
Kim, Sang-Kyun [1 ]
Nam, SeJin [2 ]
Jang, Hyunchul [1 ]
Kim, Anna [1 ]
Lee, Jeong-Ju [3 ]
机构
[1] Korea Inst Oriental Med, Mibyeong Res Ctr, Taejon, South Korea
[2] Seoul Natl Univ, Biomed Knowledge Engn Lab, Seoul, South Korea
[3] Korea Res Inst Biosci & Biotechnol, Human Derived Mat Ctr, Taejon, South Korea
来源
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE | 2015年 / 15卷
关键词
Medicinal material; Herb; Chemical compound; Ingredient; Traditional medicine; Northeast Asia; Chromatography; Curation; Database; NATURAL-PRODUCTS DATABASE; CHINESE MEDICINE; CONSTITUENTS; DISCOVERY; MECHANISM;
D O I
10.1186/s12906-015-0758-5
中图分类号
R [医药、卫生];
学科分类号
10 ;
摘要
Background: In traditional medicine, there has been a great deal of research on the effects exhibited by medicinal materials. To study the effects, resources that can systematically describe the chemical compounds in medicinal materials are necessary. In recent years, numerous databases on medicinal materials and constituent compounds have been constructed. However, because these databases provide differing information and the sources of such information are unclear or difficult to verify, it is difficult to decide which database to use. Moreover, there is much overlapping information. The aim of this study was to construct a database of medicinal materials and chemical compounds in Northeast Asian traditional medicine (TM-MC), for which medicinal materials are listed in the Korean, Chinese, and Japanese pharmacopoeias and information on the compound names of medicinal materials can easily be confirmed online. Description: To provide information on the chemical compounds of medicinal materials, chromatography articles from MEDLINE and PubMed Central were searched. After chemical compounds of medicinal materials were extracted by manually investigating the full-text of articles, a database of information on about 14,000 compounds from 536 medicinal materials was built. The database also provides links to the articles from which each medicinal material and chemical compound were extracted. Conclusion: TM-MC database provides information on medicinal materials and their chemical compounds from chromatography articles in MEDLINE and PubMed Central. Researchers can easily check relevant information through the links to articles.
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页数:8
相关论文
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