Structural Diversity and State of Knowledge of Flavonoids of the Scutellaria L. Genus

The review presents the results of scientometric analysis of data on the level of study and chemical diversity of flavonoids of the Scutellaria L. genus species of the world's flora. Flavonoid composition in 63 species of skullcap is reported, together with the data on distribution in plants, structure, and sources of 301 flavonoids belonging to the groups of flavones, flavanones, flavanonols, flavonols, chalcones, isoflavones, flavolignans, and bioflavonoids. The greatest number of flavonoids was shown to be isolated from plants of S. indica, S. baicalensis, S. barbata, S. amoena, S. prostrata, S. galericulata, S. discolor, S. ramosissima, and S. supina. Scientometric studies indicate the constantly growing interest in the study of species of the Scutellaria L. genus by scientists of various branches of science, including phytochemists, biologists, and pharmacologists. Information provided in the review can be used to address issues of chemosystematics of plants of the Scutellaria L. genus.