Corneal reconstruction is among the most effective methods for curing corneal injury due to various clinical disorders. Mesenchymal stem cells (MSCs) are a type of multipotent cells distributed in various tissues, which can be easily isolated and expanded in vitro. MSCs are self-renewable and have the potential to transdifferentiate into other type of cells under certain conditions. More recently, the modulating angiogenesis, anti-inflammatory, and immunomodulatory properties of MSCs have been confirmed in animal models. The potential roles of MSCs are valuable for corneal reconstruction. Thus, in this review, we summarized the current understanding of the possible roles of MSCs in corneal reconstruction.
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Univ Manchester, Fac Life Sci, UK Ctr Tissue Engn, Wellcome Trust Ctr Cell Matrix Res, Manchester M13 9PT, Lancs, EnglandUniv Manchester, Fac Life Sci, UK Ctr Tissue Engn, Wellcome Trust Ctr Cell Matrix Res, Manchester M13 9PT, Lancs, England
Ball, Stephen G.
Shuttleworth, C. Adrian
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Univ Manchester, Fac Life Sci, UK Ctr Tissue Engn, Wellcome Trust Ctr Cell Matrix Res, Manchester M13 9PT, Lancs, EnglandUniv Manchester, Fac Life Sci, UK Ctr Tissue Engn, Wellcome Trust Ctr Cell Matrix Res, Manchester M13 9PT, Lancs, England
Shuttleworth, C. Adrian
Kielty, Cay M.
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Univ Manchester, Fac Life Sci, UK Ctr Tissue Engn, Wellcome Trust Ctr Cell Matrix Res, Manchester M13 9PT, Lancs, EnglandUniv Manchester, Fac Life Sci, UK Ctr Tissue Engn, Wellcome Trust Ctr Cell Matrix Res, Manchester M13 9PT, Lancs, England
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Univ Manchester, Fac Life Sci, UK Ctr Tissue Engn, Wellcome Trust Ctr Cell Matrix Res, Manchester M13 9PT, Lancs, EnglandUniv Manchester, Fac Life Sci, UK Ctr Tissue Engn, Wellcome Trust Ctr Cell Matrix Res, Manchester M13 9PT, Lancs, England
Ball, Stephen G.
Shuttleworth, C. Adrian
论文数: 0引用数: 0
h-index: 0
机构:
Univ Manchester, Fac Life Sci, UK Ctr Tissue Engn, Wellcome Trust Ctr Cell Matrix Res, Manchester M13 9PT, Lancs, EnglandUniv Manchester, Fac Life Sci, UK Ctr Tissue Engn, Wellcome Trust Ctr Cell Matrix Res, Manchester M13 9PT, Lancs, England
Shuttleworth, C. Adrian
Kielty, Cay M.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Manchester, Fac Life Sci, UK Ctr Tissue Engn, Wellcome Trust Ctr Cell Matrix Res, Manchester M13 9PT, Lancs, EnglandUniv Manchester, Fac Life Sci, UK Ctr Tissue Engn, Wellcome Trust Ctr Cell Matrix Res, Manchester M13 9PT, Lancs, England