First report on the chemical composition of leaf essential oil of Myrciaria pilosa Sobral & Couto and its antimicrobial and antivirulence activities against Staphylococcus aureus

被引：13

作者：

Costa, Wendeo Kennedy ^{[1
]}

Gomes, Nandara Ohana da Costa ^{[1
]}

Souza dos Santos, Bruno ^{[1
]}

Bezerra Filho, Clovis Macedo ^{[1
]}

Oliveira, Alisson Macario de ^{[1
]}

da Silva, Graziela Claudia ^{[1
]}

Veras, Bruno Oliveira de ^{[2
]}

Oliveira, Fernanda Granja da Silva ^{[1
]}

Aguiar, Julio Cesar Ribeiro de Oliveira Farias de ^{[3
]}

Navarro, Daniela Maria do Amaral Ferraz ^{[3
]}

Correia, Maria Tereza dos Santos ^{[1
]}

Silva, Marcia Vanusa da ^{[1
]}

机构：

[1] Univ Fed Pernambuco, Dept Bioquim, Recife, PE, Brazil

[2] Univ Fed Pernambuco, Dept Med Trop, Recife, PE, Brazil

[3] Univ Fed Pernambuco, Dept Quim Fundamental, Recife, PE, Brazil

来源：

NATURAL PRODUCT RESEARCH | 2022年 / 36卷 / 09期

关键词：

Myrciaria pilosa; Myrtaceae; caatinga; sesquiterpenes; antimicrobial activity; S; aureus; CONSTITUENTS;

D O I：

10.1080/14786419.2020.1837805

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Myrciaria pilosa is a tree species of the Brazilian Caatinga biome. This paper is the first report on the chemical composition and the antimicrobial and antivirulence activities of essential oil extracted from its leaves. The oil was extracted by hydrodistillation. Chemical composition determined by GC-MS and CG-FID revealed 63 compounds; the sesquiterpenes guaiol (13.17%) and (E)-beta-caryophyllene (11.26%) dominated. Antimicrobial activity against strains of Staphylococcus aureus was evaluated by the broth microdilution method. It showed minimum inhibitory concentrations (MIC) of 5 mu g/mL against evaluated strains and minimum bactericidal concentrations (MBC) ranging from 10 to 20 mu g/mL. Evaluation of antivirulence activity showed reductions of 92.0% and 47.2%, respectively, in haemolytic action and production of staphyloxanthin. These findings show that the essential oil of M. pilosa has potential as an antimicrobial drug to control infection by multi-resistant strains of S. aureus.

引用

页码：2429 / 2433

页数：5

共 17 条

[1]

[Anonymous], 2008, Revista Brasileira Farmacognosia

[2] Microbial transformation of (-)-guaiol and antibacterial activity of its transformed products [J].

Choudhary, Muhammad Iqbal ;

Batool, Iffat ;

Atif, Muhammad ;

Hussain, Samreen ;

Atta-ur-Rahman .

JOURNAL OF NATURAL PRODUCTS, 2007, 70 (05) :849-852

[3] Essential oil from Eugenia stipitata McVaugh leaves has antinociceptive, anti-inflammatory and antipyretic activities without showing toxicity in mice [J].

Costa, Wendeo Kennedy ;

Saturnino de Oliveira, Joao Ricardhis ;

de Oliveira, Alisson Macario ;

da Silva Santos, Izabelly Bianca ;

da Cunha, Rebeca Xavier ;

Soares de Freitas, Anderson Felipe ;

Lopes Menezes da Silva, Janderson Weydson ;

Guimaraes Silva, Valquiria Bruna ;

de Oliveira Farias de Aguiar, Julio Cesar Ribeiro ;

da Silva, Alexandre Gomes ;

do Amaral Ferraz Navarro, Daniela Maria ;

de Menezes Lima, Vera Lucia ;

da Silva, Marcia Vanusa .

INDUSTRIAL CROPS AND PRODUCTS, 2020, 144

[4] The Anticancer, Antioxidant and Antimicrobial Properties of the Sesquiterpene β-Caryophyllene from the Essential Oil of Aquilaria crassna [J].

Dahham, Saad S. ;

Tabana, Yasser M. ;

Iqbal, Muhammad A. ;

Ahamed, Mohamed B. K. ;

Ezzat, Mohammed O. ;

Majid, Aman S. A. ;

Majid, Amin M. S. A. .

MOLECULES, 2015, 20 (07) :11808-11829

[5] Lupane triterpenoids, antioxidant potential and antimicrobial activity of Myrciaria floribunda (H. West ex Willd.) O. Berg. [J].

de Azevedo, Maycow Marcos L. ;

Cascaes, Marcia M. ;

Guilhon, Giselle Maria S. P. ;

Andrade, Eloisa Helena A. ;

Zoghbi, Maria das Gracas B. ;

da Silva, Joyce Kelly R. ;

Santos, Lourivaldo S. ;

da Silva, Silvia Helena M. .

NATURAL PRODUCT RESEARCH, 2019, 33 (04) :506-515

[6] Antimicrobial and Antivirulence Action of Eugenia brejoensis Essential Oil in vitro and in vivo Invertebrate Models [J].

Filho Bezerra, Clovis Macedo ;

da Silva, Luis Claudio Nascimento ;

da Silva, Marcia Vanusa ;

Lobner-Olesen, Anders ;

Struve, Carsten ;

Krogfelt, Karen Angeliki ;

Correia, Maria Tereza dos Santos ;

Oliva, Maria Luiza .

FRONTIERS IN MICROBIOLOGY, 2020, 11

[7]

Foguena Alain Kenfak, 2016, Rev Med Suisse, V12, P2026

[8] Antimicrobial constituents of peel and seeds of camu-camu (Myrciaria dubia) [J].

Kaneshima, Tai ;

Myoda, Takao ;

Toeda, Kazuki ;

Fujimori, Takane ;

Nishizawa, Makoto .

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2017, 81 (08) :1461-1465

[9] Copper activity against multiresistant Gram-positive cocci isolated in Chilean hospitals [J].

Kappes, Tomas ;

Dominguez, Mariana ;

Bello-Toledo, Helia ;

Montecinos, Sergio Melia ;

Molina, Gisella Riedel ;

Gonzalez-Rocha, Gerardo .

REVISTA CHILENA DE INFECTOLOGIA, 2016, 33 (05) :519-523

[10] Vapour phase: a potential future use for essential oils as antimicrobials? [J].

Laird, K. ;

Phillips, C. .

LETTERS IN APPLIED MICROBIOLOGY, 2012, 54 (03) :169-174

← 1 2 →